{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:24:32Z","timestamp":1740137072152,"version":"3.37.3"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,1,28]],"date-time":"2017-01-28T00:00:00Z","timestamp":1485561600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2017,3]]},"abstract":"Background<\/jats:title>Longitudinal motion of the mitral annulus is an index that reflects left ventricular (LV<\/jats:styled-content>) function. The aim of this study was to evaluate and compare the effects of transcatheter mitral valve (MV<\/jats:styled-content>) repair and open heart surgery for mitral regurgitation (MR<\/jats:styled-content>) on mitral annular motion (MAM<\/jats:styled-content>).<\/jats:p><\/jats:sec>Methods<\/jats:title>We retrospectively analyzed in total 115 patients who underwent isolated transcatheter MV<\/jats:styled-content> repair using MitraClip (n=50) or surgical MV<\/jats:styled-content> interventions (n=65, 50 repairs and 15 replacements) for MR<\/jats:styled-content>. MAM<\/jats:styled-content> was assessed by two\u2010dimensional B\u2010mode echocardiography in the four\u2010 and two\u2010chamber views. MAM<\/jats:styled-content> was measured before and within 1\u00a0month after the mitral procedure.<\/jats:p><\/jats:sec>Results<\/jats:title>Compared with patients undergoing MV<\/jats:styled-content> surgery, patients undergoing the MitraClip procedure were older and had more comorbidities. MR<\/jats:styled-content> grade improved significantly in both groups after MV<\/jats:styled-content> intervention. MAM<\/jats:styled-content> decreased significantly in the surgery group (12.0\u00b13.1 to 8.1\u00b12.2\u00a0mm, P<\/jats:italic><.01), whereas MAM<\/jats:styled-content> did not change in the MitraClip group (8.8\u00b12.6 to 8.6\u00b12.5\u00a0mm, P<\/jats:italic>=.59). In multivariate analysis, mitral surgery was associated with a decrease in MAM<\/jats:styled-content> when compared to the MitraClip procedure. Furthermore, LV<\/jats:styled-content> ejection fraction (EF<\/jats:styled-content>) decreased to a greater degree in patients undergoing surgery than those undergoing MitraClip placement (MV<\/jats:styled-content> surgery; \u221210.1\u00b17.6% vs MitraClip; \u22123.0\u00b110.5%, P<\/jats:italic><.01).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>MitraClip therapy does not adversely influence MAM<\/jats:styled-content> and is associated with less postprocedural EF<\/jats:styled-content> reduction compared to surgical intervention. Our results suggest that patients with reduced LV<\/jats:styled-content> systolic function may benefit from the MitraClip procedure compared to mitral surgery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13459","type":"journal-article","created":{"date-parts":[[2017,1,28]],"date-time":"2017-01-28T05:34:10Z","timestamp":1485581650000},"page":"334-339","source":"Crossref","is-referenced-by-count":2,"title":["Mitral annular motion in patients after transcatheter MitraClip and mitral valve surgery"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7083-0371","authenticated-orcid":false,"given":"Kentaro","family":"Toyama","sequence":"first","affiliation":[{"name":"The Heart Institute Cedars\u2010Sinai Medical Center Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Rader","sequence":"additional","affiliation":[{"name":"The Heart Institute Cedars\u2010Sinai Medical Center Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kengo","family":"Ayabe","sequence":"additional","affiliation":[{"name":"Department of Anesthesia Cedars\u2010Sinai Medical Center Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saibal","family":"Kar","sequence":"additional","affiliation":[{"name":"The Heart Institute Cedars\u2010Sinai Medical Center Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Trento","sequence":"additional","affiliation":[{"name":"The Heart Institute Cedars\u2010Sinai Medical Center Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiko","family":"Nishioka","sequence":"additional","affiliation":[{"name":"Department of Cardiology Saitama Medical Center Saitama Medical University Kawagoe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele A.","family":"De Robertis","sequence":"additional","affiliation":[{"name":"The Heart Institute Cedars\u2010Sinai Medical Center Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert J.","family":"Siegel","sequence":"additional","affiliation":[{"name":"The Heart Institute Cedars\u2010Sinai Medical Center Los Angeles CA 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