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In patients with <jats:styled-content style=\"fixed-case\">LVH<\/jats:styled-content>, subclinical left ventricular (<jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content>) dysfunction despite normal ejection fraction (<jats:styled-content style=\"fixed-case\">EF<\/jats:styled-content>) may be present before the onset of symptoms, which portends a dismal prognosis. Strain measurement with two\u2010dimensional speckle tracking echocardiography (<jats:styled-content style=\"fixed-case\">STE<\/jats:styled-content>) represents a highly reproducible and accurate alternative to <jats:styled-content style=\"fixed-case\">LVEF<\/jats:styled-content> determination. The present review focuses on current available evidence that supports the incremental value of <jats:styled-content style=\"fixed-case\">STE<\/jats:styled-content> in the diagnostic and prognostic workup of <jats:styled-content style=\"fixed-case\">LVH<\/jats:styled-content>. When assessing the components of <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> contraction, <jats:styled-content style=\"fixed-case\">STE<\/jats:styled-content> has an incremental value in differentiating between primary and secondary <jats:styled-content style=\"fixed-case\">LVH<\/jats:styled-content> and in the differential diagnosis with storage diseases. In addition, <jats:styled-content style=\"fixed-case\">STE<\/jats:styled-content> provides unique information for the stratification of patients with <jats:styled-content style=\"fixed-case\">LVH<\/jats:styled-content>, enabling to detect intrinsic myocardial dysfunction before <jats:styled-content style=\"fixed-case\">LVEF<\/jats:styled-content> reduction.<\/jats:p>","DOI":"10.1111\/echo.13506","type":"journal-article","created":{"date-parts":[[2017,3,20]],"date-time":"2017-03-20T04:37:02Z","timestamp":1489984622000},"page":"746-759","source":"Crossref","is-referenced-by-count":35,"title":["Left ventricular hypertrophy or storage disease? the incremental value of speckle tracking strain bull's\u2010eye"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9698-9145","authenticated-orcid":false,"given":"Antonello","family":"D'Andrea","sequence":"first","affiliation":[{"name":"Monaldi Hospital Second University of Naples  Naples 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