{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T10:36:21Z","timestamp":1787740581434,"version":"build-2784847793"},"reference-count":41,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T00:00:00Z","timestamp":1493164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>In this study, we investigated whether mechanical dispersion which reflects electrical abnormality and other echocardiographic and clinic parameters predict appropriate <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content> shock in patients undergone <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content> implantation for hypertrophic cardiomyopathy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty\u2010three patients who received <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content> implantation for primary or secondary prevention were included in the study. Patients\u2019 clinical, electrocardiographic, 2D classic, and speckle tracking echocardiographic data were collected. Mechanical dispersion was defined as the standard deviation of time to peak negative strain in 18 left ventricular segments. Appropriate <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content> therapy was defined as cardioversion or defibrillation due to ventricular tachycardia or fibrillation. Patients were divided into two groups as occurrence or the absence of appropriate <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content> therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 17 (26.9%) patients were observed to have an appropriate <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content> therapy during follow\u2010up periods. In patients who performed appropriate <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content> therapy, a larger left atrial volume index, higher sudden cardiac death (<jats:styled-content style=\"fixed-case\">SCD<\/jats:styled-content>)\u2010Risk Score, longer mechanical dispersion, and decreased global longitudinal peak strain (<jats:styled-content style=\"fixed-case\">GLPS<\/jats:styled-content>) were observed. In multivariate logistic regression analysis, including (<jats:styled-content style=\"fixed-case\">GLPS<\/jats:styled-content>, mechanical dispersion, <jats:styled-content style=\"fixed-case\">LAV<\/jats:styled-content>i, and SCD\u2010Risk Score) was used to determine independent predictors of occurrence of appropriate <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content> therapy during the follow\u2010up. Mechanical dispersion, <jats:styled-content style=\"fixed-case\">GLPS<\/jats:styled-content>, and SCD\u2010Risk Score were found to be independent predictors of\u00a0occurrence of appropriate <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content> therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Mechanical dispersion, GLPS, and SCD\u2010Risk Score were found to be predictive for appropriate <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content> therapy in patients receiving <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content> implantation. Readily measurable mechanical dispersion and <jats:styled-content style=\"fixed-case\">GLPS<\/jats:styled-content> could be helpful to distinguish patients at high risk who could optimally benefit from <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content> therapy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13547","type":"journal-article","created":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T07:49:40Z","timestamp":1493192980000},"page":"835-842","source":"Crossref","is-referenced-by-count":38,"title":["Mechanical dispersion and global longitudinal strain by speckle tracking echocardiography: Predictors of appropriate implantable cardioverter defibrillator therapy in hypertrophic cardiomyopathy"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7700-645X","authenticated-orcid":false,"given":"Ozkan","family":"Candan","sequence":"first","affiliation":[{"name":"Cardiology Clinic Kartal Kosuyolu Training and Research Hospital  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