{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T23:42:20Z","timestamp":1771630940380,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,7,18]],"date-time":"2017-07-18T00:00:00Z","timestamp":1500336000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>An association between cardiomyopathy and celiac disease has been reported, but not frequently. We examined the effects on cardiac mechanics in children with celiac disease (CD) by two\u2010dimensional speckle tracking echocardiography (2DSTE).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighty\u2010one children with CD were compared with a control group comprising 51 healthy children by echocardiographic examination. Children with CD who had been on gluten\u2010free diet for more than 6\u00a0months were divided into two different groups: group 1 was positive for serum antitissue transglutaminase antibody (n=48), and group 2 was negative for serum antitissue transglutaminase antibody (n=33). Cardiac functions were evaluated in all children using conventional echocardiography, tissue Doppler imaging (TDI), and 2DSTE methods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For children with CD, the mean age and male:female ratio were 10.1\u00b14.0\u00a0years and 26\/55 (67% female), respectively, which did not differ from the controls. Patients were diagnosed at a mean age of 7.9\u00b14.1\u00a0years, and the mean follow\u2010up time was 2.37\u00b12.98\u00a0years. Conventional echocardiography and TDI measurements did not differ between groups. The left ventricular longitudinal and radial strains, and strain rate values were significantly lower in patients with CD, particularly in those with positive antitissue transglutaminase antibody compared with the control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our results suggest that 2DSTE is superior to conventional and TDI echocardiography for evaluating subclinical carditis in children with CD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13624","type":"journal-article","created":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T01:58:58Z","timestamp":1500429538000},"page":"1339-1346","source":"Crossref","is-referenced-by-count":6,"title":["Left ventricular mechanics are affected in children with celiac disease: A study based on two\u2010dimensional speckle tracking echocardiography"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6246-671X","authenticated-orcid":false,"given":"Murat","family":"Deveci","sequence":"first","affiliation":[{"name":"Department of Pediatric Cardiology Kocaeli University Medical Faculty  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ay\u015fen","family":"Uncuo\u011flu Aydo\u011fan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology Kocaeli University Medical Faculty  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fcrkan","family":"Altun","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Derince Training and Research Hospital  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zlem","family":"Kayabey","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Kocaeli University Medical Faculty  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Okan","family":"Tu\u011fral","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Kocaeli University Medical Faculty  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kadir","family":"Babao\u011flu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Kocaeli University Medical Faculty  Kocaeli 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