{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T14:04:33Z","timestamp":1793109873431,"version":"4.5.0"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,10,10]],"date-time":"2017-10-10T00:00:00Z","timestamp":1507593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002799","name":"Capital Medical University","doi-asserted-by":"publisher","award":["16JL39"],"award-info":[{"award-number":["16JL39"]}],"id":[{"id":"10.13039\/501100002799","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2018,1]]},"abstract":"Background<\/jats:title>It has been reported that congenital heart disease with decreased pulmonary blood flow (CHD<\/jats:styled-content>\u2010DPBF<\/jats:styled-content>) may affect postnatal lung morphogenesis and function. However, there has been a lack of information regarding the impact of CHD<\/jats:styled-content>\u2010DPBF<\/jats:styled-content> on prenatal fetal lung development.<\/jats:p><\/jats:sec>Methods<\/jats:title>Fifty\u2010four fetuses with CHD<\/jats:styled-content>\u2010DPBF<\/jats:styled-content> were compared with 110 controls. Fetal lung volume (FLV<\/jats:styled-content>) was estimated using three\u2010dimensional ultrasonography (3D\u2010US<\/jats:styled-content>). Estimated fetal weight (EFW<\/jats:styled-content>) and McGoon index (MGI<\/jats:styled-content>) were estimated using two\u2010dimensional ultrasonography (2D\u2010US<\/jats:styled-content>).<\/jats:p><\/jats:sec>Results<\/jats:title>FLV<\/jats:styled-content>\/EFW<\/jats:styled-content> and MGI<\/jats:styled-content> values measured using sonography for the CHD<\/jats:styled-content>\u2010DPBF<\/jats:styled-content> group were significantly reduced compared to those of the control group (P\u00a0<\/jats:italic><\u00a0<\/jats:italic>.05). Pearson correlation analysis indicated that the summed diameter of the right pulmonary artery and left pulmonary artery (RPA<\/jats:styled-content>\u00a0+\u00a0LPA<\/jats:styled-content>) measured by 2D\u2010US<\/jats:styled-content> correlated well with FLV<\/jats:styled-content> measured by 3D\u2010US<\/jats:styled-content>.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>In our study, FLV<\/jats:styled-content>\/EFW<\/jats:styled-content> and MGI<\/jats:styled-content> values for fetuses with CHD<\/jats:styled-content>\u2010DPBF<\/jats:styled-content> tended to be decreased and FLV<\/jats:styled-content> was associated with RPA<\/jats:styled-content>\u00a0+\u00a0LPA<\/jats:styled-content>. We concluded that CHD<\/jats:styled-content>\u2010DPBF<\/jats:styled-content> might delay fetal lung development. The summed diameter of the RPA<\/jats:styled-content>\u00a0+\u00a0LPA<\/jats:styled-content> measurement could be used as an alternative to FLV<\/jats:styled-content> for assessing fetal lung development.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13724","type":"journal-article","created":{"date-parts":[[2017,10,10]],"date-time":"2017-10-10T05:22:48Z","timestamp":1507612968000},"page":"85-89","source":"Crossref","is-referenced-by-count":12,"title":["Fetal lung volume and pulmonary artery changes in congenital heart disease with decreased pulmonary blood flow: Quantitative ultrasound analysis"],"prefix":"10.1111","volume":"35","author":[{"given":"Yong","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Ultrasound Beijing Key Laboratory of Maternal\u2010Fetal Medicine in Fetal Heart Disease Beijing An Zhen Hospital Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaowei","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Beijing Key Laboratory of Maternal\u2010Fetal Medicine in Fetal Heart Disease Beijing An Zhen Hospital Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Beijing Key Laboratory of Maternal\u2010Fetal Medicine in Fetal Heart Disease Beijing An Zhen Hospital Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Beijing Key Laboratory of Maternal\u2010Fetal Medicine in Fetal Heart Disease Beijing An Zhen Hospital Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Beijing Key Laboratory of Maternal\u2010Fetal Medicine in Fetal Heart Disease Beijing An Zhen Hospital Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6857-3516","authenticated-orcid":false,"given":"Yihua","family":"He","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Beijing Key Laboratory of Maternal\u2010Fetal Medicine in Fetal Heart Disease Beijing An Zhen Hospital Capital Medical University Beijing 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