{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T20:47:43Z","timestamp":1762980463252,"version":"3.37.3"},"reference-count":7,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T00:00:00Z","timestamp":1508976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:p>Anterior mitral valve leaflet (<jats:styled-content style=\"fixed-case\">AMVL<\/jats:styled-content>) perforation is most commonly seen in the setting of infective endocarditis. We present a case of <jats:styled-content style=\"fixed-case\">AMVL<\/jats:styled-content> perforation in a previously healthy 62\u2010year\u2010old male who presented with a six\u2010month history of worsening dyspnea and peripheral edema. Blood cultures, inflammatory markers, and autoimmune profile were negative. Transthoracic echocardiography demonstrated severe mitral regurgitation (<jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>) with a possible <jats:styled-content style=\"fixed-case\">AMVL<\/jats:styled-content> perforation, which was confirmed by three\u2010dimensional transesophageal echocardiography as a well\u2010circumscribed hole in the A2 segment. The patient made a successful recovery from mitral valve repair surgery.<\/jats:p>","DOI":"10.1111\/echo.13734","type":"journal-article","created":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T08:18:35Z","timestamp":1509005915000},"page":"1953-1955","source":"Crossref","is-referenced-by-count":7,"title":["Anterior mitral valve perforation in the absence of acute infection: Diagnosis by two\u2010dimensional and three\u2010dimensional transesophageal echocardiography"],"prefix":"10.1111","volume":"34","author":[{"given":"Mary","family":"Mashicharan","sequence":"first","affiliation":[{"name":"Department of Cardiology University Hospital Southampton  Southampton United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter J.","family":"Cowburn","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospital Southampton  Southampton United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven A.","family":"Livesey","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery University Hospital Southampton  Southampton United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9681-7311","authenticated-orcid":false,"given":"Benoy N.","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospital Southampton  Southampton United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,10,26]]},"reference":[{"key":"e_1_2_3_2_1","first-page":"103","article-title":"Severe mitral regurgitation due to perforation of anterior mitral leaflet","volume":"9","author":"Karabinos I","year":"2008","journal-title":"Eur Heart J Cardiovasc Img"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jex018"},{"key":"e_1_2_3_4_1","first-page":"1","article-title":"A rare case of spontaneous mitral leaflet perforation leading to severe mitral regurgitation","volume":"1","author":"Ari A","year":"2016","journal-title":"Ind J Cardiovasc Dis Women"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2015.06.027"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2007.08.048"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10034-1027"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(01)03419-1"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecho.13734","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.13734","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T00:00:36Z","timestamp":1696032036000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.13734"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,26]]},"references-count":7,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["10.1111\/echo.13734"],"URL":"https:\/\/doi.org\/10.1111\/echo.13734","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"type":"print","value":"0742-2822"},{"type":"electronic","value":"1540-8175"}],"subject":[],"published":{"date-parts":[[2017,10,26]]}}}