{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:20:24Z","timestamp":1762507224148,"version":"3.37.3"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,11,8]],"date-time":"2017-11-08T00:00:00Z","timestamp":1510099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>The restrictive mitral valve annuloplasty (<jats:styled-content style=\"fixed-case\">RMA<\/jats:styled-content>) is the treatment of choice for degenerative mitral regurgitation (<jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>), but postoperative functional mitral stenosis remains a matter of debate. In this study, we sought to determine the impact of mitral stenosis on the functional capacity of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a cross\u2010sectional study, 32 patients with degenerative <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content> who underwent <jats:styled-content style=\"fixed-case\">RMA<\/jats:styled-content> using a complete ring were evaluated. All participants performed treadmill exercise test and underwent echocardiographic examinations before and after exercise.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The patients\u2019 mean age was 50.1\u00a0\u00b1\u00a012.5\u00a0years. After a mean follow\u2010up of 14.1\u00a0\u00b1\u00a05.9\u00a0months (6\u201332\u00a0months), the number of patients with a mitral valve peak gradient &gt;7.5\u00a0mm\u00a0Hg, a mitral valve mean gradient &gt;3\u00a0mm\u00a0Hg, and a pulmonary arterial pressure (PAP) \u226525\u00a0mm\u00a0Hg at rest were 50%, 40.6%, and 62.5%, respectively. 13 patients (40.6%) had incomplete treadmill exercise test. All hemodynamic parameters were higher at peak exercise compared with at rest levels (all <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.05). The <jats:styled-content style=\"fixed-case\">PAP<\/jats:styled-content> at rest and at peak exercise as well as peak transmitral gradient at peak exercise were higher in patients with incomplete exercise compared with complete exercise test (all <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.05). The <jats:styled-content style=\"fixed-case\">PAP<\/jats:styled-content> at rest (a sensitivity and a specificity of 84.6% and 52.6%, respectively; area under the curve [<jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content>]\u00a0=\u00a0.755) and at peak exercise (a sensitivity and a specificity of 100% and 47.4%, respectively; <jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content>\u00a0=\u00a0.755) discriminated incomplete exercise test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">RMA<\/jats:styled-content> for degenerative <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content> was associated with a functional stenosis and the <jats:styled-content style=\"fixed-case\">PAP<\/jats:styled-content> at rest and at peak exercise discriminated low exercise capacity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13744","type":"journal-article","created":{"date-parts":[[2017,11,8]],"date-time":"2017-11-08T08:52:11Z","timestamp":1510131131000},"page":"211-217","source":"Crossref","is-referenced-by-count":5,"title":["Pulmonary arterial pressure detects functional mitral stenosis after annuloplasty for primary mitral regurgitation: An exercise stress echocardiographic study"],"prefix":"10.1111","volume":"35","author":[{"given":"Niloufar","family":"Samiei","sequence":"first","affiliation":[{"name":"Heart Valve Disease Research Center Rajaie Cardiovascular Medical and Research Center Iran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marzieh","family":"Tajmirriahi","sequence":"additional","affiliation":[{"name":"Hypertension Research Center Isfahan Cardiovascular Research Institute Isfahan University of Medical Sciences  Isfahan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Rafati","sequence":"additional","affiliation":[{"name":"Heart Valve Disease Research Center Rajaie Cardiovascular Medical and Research Center Iran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yeganeh","family":"Pasebani","sequence":"additional","affiliation":[{"name":"Heart Valve Disease Research Center Rajaie Cardiovascular Medical and Research Center Iran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6804-4232","authenticated-orcid":false,"given":"Yousef","family":"Rezaei","sequence":"additional","affiliation":[{"name":"Heart Valve Disease Research Center Rajaie Cardiovascular Medical and Research Center Iran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saeid","family":"Hosseini","sequence":"additional","affiliation":[{"name":"Heart Valve Disease Research Center Rajaie Cardiovascular Medical and Research Center Iran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,11,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69208-8"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.07.062"},{"key":"e_1_2_6_4_1","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1016\/j.jtcvs.2015.03.003","article-title":"Determinants of functional capacity after mitral valve annuloplasty or replacement for ischemic mitral regurgitation","volume":"149","author":"Fino C","year":"2015","journal-title":"J Thorac Cardiovasc 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