{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T05:18:53Z","timestamp":1761110333161,"version":"3.37.3"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,11,26]],"date-time":"2017-11-26T00:00:00Z","timestamp":1511654400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2018,2]]},"abstract":"Aims<\/jats:title>Left bundle branch block (LBBB<\/jats:styled-content>) causes a dyssynchronized contraction of left ventricle. This is a kind of regional wall\u2010motion abnormality and measuring left ventricular ejection fraction (LVEF<\/jats:styled-content>) by two\u2010dimensional (2D) echocardiography could be less reliable in this particular condition. Our aim was to evaluate the role of dyssynchrony index (SDI<\/jats:styled-content>), measured by three\u2010dimensional (3D) echocardiography, in assessment of LVEF<\/jats:styled-content> and left ventricular volumes accurately in patients with LBBB<\/jats:styled-content>.<\/jats:p><\/jats:sec>Methods and Results<\/jats:title>In this case\u2013control study, we included 52 of 64 enrolled participants (twelve participants with poor image quality were excluded) with LBBB<\/jats:styled-content> and normal LVEF<\/jats:styled-content> or nonischemic cardiomyopathy. Left ventricular ejection fraction (LVEF<\/jats:styled-content>) and left ventricular volumes were assessed by 2D (modified Simpson's rule) and 3D (four beats full volume analysis) echocardiography and the impact of SDI<\/jats:styled-content> on results were evaluated. In patients with SDI<\/jats:styled-content> \u22656%, LVEF<\/jats:styled-content> measurements were significantly different (46.00% [29.50\u201352.50] vs 37.60% [24.70\u201345.15], P<\/jats:italic>\u00a0<\u00a0.001) between 2D and 3D echocardiography, respectively. In patients with SDI<\/jats:styled-content>\u00a0<\u00a06%, there were no significant differences between two modalities in terms of LVEF<\/jats:styled-content> measurements (54.50% [49.00\u201359.00] vs 54.25% [40.00\u201358.25], P<\/jats:italic>\u00a0=\u00a0.193). LV<\/jats:styled-content> diastolic volumes were not significantly different while systolic volumes were underestimated by 2D echocardiography, and this finding was more pronounced when SDI<\/jats:styled-content>\u00a0\u2265\u00a06%.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>In patients with LBBB<\/jats:styled-content> and high SDI<\/jats:styled-content> (\u22656%), LVEF<\/jats:styled-content> values were overestimated and systolic volumes were underestimated by 2D echocardiography compared to 3D echocardiography.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13758","type":"journal-article","created":{"date-parts":[[2017,11,26]],"date-time":"2017-11-26T18:02:43Z","timestamp":1511719363000},"page":"148-152","source":"Crossref","is-referenced-by-count":2,"title":["Do we overestimate left ventricular ejection fraction by two\u2010dimensional echocardiography in patients with left bundle branch block?"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5549-3744","authenticated-orcid":false,"given":"Ali K.","family":"Cabuk","sequence":"first","affiliation":[{"name":"Department of Cardiology Tepecik Training and Research Hospital Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gizem","family":"Cabuk","sequence":"additional","affiliation":[{"name":"Department of Cardiology Buca Seyfidemirsoy State Hospital Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Sayin","sequence":"additional","affiliation":[{"name":"Department of Cardiology Tepecik Training and Research Hospital Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"Karamanlioglu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Beypazari State Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bar\u0131\u015f","family":"Kilicaslan","sequence":"additional","affiliation":[{"name":"Department of Cardiology Tepecik Training and Research Hospital Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cenk","family":"Ekmekci","sequence":"additional","affiliation":[{"name":"Department of Cardiology Tepecik Training and Research Hospital Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatice","family":"Solmaz","sequence":"additional","affiliation":[{"name":"Department of Cardiology Tepecik Training and Research Hospital Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omer F.","family":"Aslanturk","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kusadasi State Hospital Aydin Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oner","family":"Ozdogan","sequence":"additional","affiliation":[{"name":"Department of Cardiology Tepecik Training and Research Hospital Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,11,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jev014"},{"key":"e_1_2_5_3_1","doi-asserted-by":"crossref","DOI":"10.5005\/jp\/books\/11889","volume-title":"Comprehensive Textbook of Echocardiography","author":"Nanda NC","year":"2014"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi666"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-90-3-303"},{"key":"e_1_2_5_6_1","first-page":"40","article-title":"Evaluation of global left ventricular function and mechanical dyssynchrony in patients with an asymptomatic left bundle branch block: a real\u2010time 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