{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T19:02:08Z","timestamp":1775242928012,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T00:00:00Z","timestamp":1520294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>Paroxysmal atrial fibrillation (<jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content>) commonly recurs after radiofrequency catheter ablation (<jats:styled-content style=\"fixed-case\">RFCA<\/jats:styled-content>). This study aimed to assess left atrial appendage (<jats:styled-content style=\"fixed-case\">LAA<\/jats:styled-content>) volume and function by transesophageal echocardiography (<jats:styled-content style=\"fixed-case\">TEE<\/jats:styled-content>) and to explore its value in predicting <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content> recurrence after <jats:styled-content style=\"fixed-case\">RFCA<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighty patients with <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content> were recruited. The left atrial (<jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>) and <jats:styled-content style=\"fixed-case\">LAA<\/jats:styled-content> volume and function were measured by transthoracic echocardiography (<jats:styled-content style=\"fixed-case\">TTE<\/jats:styled-content>) and <jats:styled-content style=\"fixed-case\">TEE<\/jats:styled-content> before ablation. Patients were followed up for 12\u00a0months after <jats:styled-content style=\"fixed-case\">RFCA<\/jats:styled-content>, and recurrence was recorded. Odds ratios of candidate risk indicators were determined by logistic regression analysis. Prediction model was constructed using logistic regression with backward selection. Receiver operating characteristic (<jats:styled-content style=\"fixed-case\">ROC<\/jats:styled-content>) curve with area under curve (<jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content>) was performed to evaluate the prediction efficiency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010four (30%) <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content> patients had recurrence (R group), and 56 (70%) patients had no recurrence (<jats:styled-content style=\"fixed-case\">NR<\/jats:styled-content> group). Compared to <jats:styled-content style=\"fixed-case\">NR<\/jats:styled-content> group, <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> dimension (<jats:styled-content style=\"fixed-case\">LAD<\/jats:styled-content>), <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> volume index (<jats:styled-content style=\"fixed-case\">LAVI<\/jats:styled-content>), <jats:styled-content style=\"fixed-case\">LAA<\/jats:styled-content> maximum volume (<jats:styled-content style=\"fixed-case\">LAAV<\/jats:styled-content>max), and <jats:styled-content style=\"fixed-case\">LAA<\/jats:styled-content> minimum volume (<jats:styled-content style=\"fixed-case\">LAAV<\/jats:styled-content>min) were significantly higher in R group, while <jats:styled-content style=\"fixed-case\">LAA<\/jats:styled-content> peak emptying flow velocity (<jats:styled-content style=\"fixed-case\">LAA<\/jats:styled-content>eV), <jats:styled-content style=\"fixed-case\">LAA<\/jats:styled-content> peak filling flow velocity (<jats:styled-content style=\"fixed-case\">LAA<\/jats:styled-content>fV), and <jats:styled-content style=\"fixed-case\">LAA<\/jats:styled-content> ejection fraction (<jats:styled-content style=\"fixed-case\">LAAEF<\/jats:styled-content>) significantly declined in R group. According to multivariate analysis and backward selection, <jats:styled-content style=\"fixed-case\">LAVI<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> LAAEF<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">LAA<\/jats:styled-content>eV were significant risk factors for <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content> recurrence. The <jats:styled-content style=\"fixed-case\">LAVI<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">LAAEF<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">LAA<\/jats:styled-content>eV joint model could effectively predict <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content> recurrence with <jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content> of 0.893 (95% confidence interval\u00a0=\u00a00.816, 0.970), sensitivity of 0.75, and specificity of 0.929.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study demonstrated that <jats:styled-content style=\"fixed-case\">LAVI<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> LAAEF<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">LAA<\/jats:styled-content>eV were significant predictors of <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content> recurrence after <jats:styled-content style=\"fixed-case\">RFCA<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13856","type":"journal-article","created":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T19:32:41Z","timestamp":1520364761000},"page":"985-990","source":"Crossref","is-referenced-by-count":26,"title":["Transesophageal echocardiography measures left atrial appendage volume and function and predicts recurrence of paroxysmal atrial fibrillation after radiofrequency catheter ablation"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1326-2793","authenticated-orcid":false,"given":"Yemei","family":"He","sequence":"first","affiliation":[{"name":"Department of Medical Ultrasonics The Third Xiangya Hospital of Central South University  Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baixue","family":"Zhang","sequence":"additional","affiliation":[{"name":"Zhuhai City People's Hospital  Zhuhai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasonics The Third Xiangya Hospital of Central South University  Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zheyu","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Breast Medical Oncology The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University  Changsha China"},{"name":"Department of Experiment and Laboratory The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University  Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasonics The Third Xiangya Hospital of Central South University  Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenhui","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasonics The Third Xiangya Hospital of Central South University  Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,6]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198204293061703"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.18.2370"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1987.00370090041008"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.772582"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2012.09.002"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.12823"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2013.11.015"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2005.09516.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2004.03538.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eus027"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/HCO.0000000000000027"},{"key":"e_1_2_5_13_1","first-page":"609","article-title":"[Commentary to the article: Wilber DJ, Pappone C, Neuzil P et al. 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