{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T13:43:44Z","timestamp":1792590224546,"version":"4.5.0"},"reference-count":26,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T00:00:00Z","timestamp":1534982400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008666","name":"Fundaci\u00f3 la Marat\u00f3 de TV3","doi-asserted-by":"publisher","award":["201502"],"award-info":[{"award-number":["201502"]}],"id":[{"id":"10.13039\/100008666","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008666","name":"Fundaci\u00f3 la Marat\u00f3 de TV3","doi-asserted-by":"publisher","award":["201516"],"award-info":[{"award-number":["201516"]}],"id":[{"id":"10.13039\/100008666","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2018,11]]},"abstract":"\n Background<\/jats:title>\n \n Pulmonary hypertension (\n PH<\/jats:styled-content>\n ) is a common cause of right ventricular (\n RV<\/jats:styled-content>\n ) remodeling and functional tricuspid regurgitation (\n FTR<\/jats:styled-content>\n ), but incremental pulmonary artery systolic pressure (\n PASP<\/jats:styled-content>\n ) does not always correlate with anatomic and functional\n RV<\/jats:styled-content>\n changes. This study aimed to evaluate a noninvasive measure of pulmonary vascular resistance (\n PVR<\/jats:styled-content>\n ) for predicting\n RV<\/jats:styled-content>\n dilatation,\n RV<\/jats:styled-content>\n dysfunction, and severity of\n FTR<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n We prospectively analyzed consecutive stable patients with\n PASP<\/jats:styled-content>\n \u00a0\u2265\u00a035\u00a0mm\u00a0Hg or any degree of\n RV<\/jats:styled-content>\n dilatation or dysfunction secondary to\n PH<\/jats:styled-content>\n . Noninvasive\n PVR<\/jats:styled-content>\n was calculated based on\n FTR<\/jats:styled-content>\n peak velocity and flow in\n RV<\/jats:styled-content>\n outflow tract.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n We included 251 patients, aged 72.1\u00a0\u00b1\u00a011.4\u00a0years, 53% women, 74.9% with type 2 pulmonary hypertension. The mean\n PASP<\/jats:styled-content>\n was 48.3\u00a0\u00b1\u00a012.2\u00a0mm\u00a0Hg. Both\n PASP<\/jats:styled-content>\n and\n PVR<\/jats:styled-content>\n significantly correlated with\n FTR<\/jats:styled-content>\n ,\n RV<\/jats:styled-content>\n dilatation, and\n RV<\/jats:styled-content>\n systolic dysfunction. After dichotomizing\n FTR<\/jats:styled-content>\n and\n RV<\/jats:styled-content>\n dilatation and systolic dysfunction as nonsignificant vs significant,\n FTR<\/jats:styled-content>\n and\n RV<\/jats:styled-content>\n dilatation were similarly predicted by\n PASP<\/jats:styled-content>\n and\n PVR<\/jats:styled-content>\n , but\n RV<\/jats:styled-content>\n dysfunction was better predicted by\n PVR<\/jats:styled-content>\n (\n AUC<\/jats:styled-content>\n \u00a0=\u00a00.78 [0.72\u20130.84] vs 0.66 [0.60\u20130.73] for\n PASP<\/jats:styled-content>\n ,\n P\u00a0<\/jats:italic>\n <\n \u00a0<\/jats:italic>\n 0.001). Patients with low\n PASP<\/jats:styled-content>\n but high\n PVR<\/jats:styled-content>\n showed worse\n RV<\/jats:styled-content>\n and left ventricular function but lower rates of right heart failure and smaller inferior vena cava, compared to patients with high\n PASP<\/jats:styled-content>\n but low\n PVR<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Noninvasive\n PVR<\/jats:styled-content>\n was superior to\n PASP<\/jats:styled-content>\n for predicting\n RV<\/jats:styled-content>\n systolic dysfunction, but both were similarly associated with\n RV<\/jats:styled-content>\n dilatation or\n FTR<\/jats:styled-content>\n grade.\n PASP<\/jats:styled-content>\n and\n PVR<\/jats:styled-content>\n complement each other to define the echocardiographic findings and clinical status of the patient.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/echo.14125","type":"journal-article","created":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T06:29:16Z","timestamp":1535005756000},"page":"1736-1745","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Pulmonary vascular resistance versus pulmonary artery pressure for predicting right ventricular remodeling and functional tricuspid regurgitation"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5144-9081","authenticated-orcid":false,"given":"Francisco","family":"Gual\u2010Capllonch","sequence":"first","affiliation":[{"name":"Heart Institute Hospital Universitari Germans Trias i Pujol Badalona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Teis","sequence":"additional","affiliation":[{"name":"Heart Institute Hospital Universitari Germans Trias i Pujol Badalona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Ferrer","sequence":"additional","affiliation":[{"name":"Heart Institute Hospital Universitari Germans Trias i Pujol Badalona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio","family":"N\u00fa\u00f1ez","sequence":"additional","affiliation":[{"name":"CIBERCV Instituto de Salud Carlos III Madrid Spain"},{"name":"Cardiology Department Hospital Cl\u00ednico Universitario INCLIVA Valencia Valencia Spain"},{"name":"Department of Medicine Universidad de Valencia Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria","family":"Vallejo","sequence":"additional","affiliation":[{"name":"Heart Institute Hospital Universitari Germans Trias i Pujol Badalona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gladys","family":"Junc\u00e0","sequence":"additional","affiliation":[{"name":"Heart Institute Hospital Universitari Germans Trias 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