{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:27:12Z","timestamp":1791419232739,"version":"4.3.3"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,12,4]],"date-time":"2018-12-04T00:00:00Z","timestamp":1543881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2019,2]]},"abstract":"\n Background and Aim<\/jats:title>\n \n Stable angina pectoris is a common disease that may cause disability. Some noninvasive new methods can be useful for the detection of early\u2010stage coronary artery disease. The relationship between coronary artery disease (\n CAD<\/jats:styled-content>\n ) severity and resting 3\u2010dimensional\u2010speckle tracking echocardiography (3D\u2010\n STE<\/jats:styled-content>\n ) in stable angina pectoris patients was evaluated in this study.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n One hundred and twenty consecutive patients between 18\u201380\u00a0years of age and without a history of\n CAD<\/jats:styled-content>\n to whom elective coronary angiography was planned after positive stress test or myocardial perfusion scintigraphy were enrolled in the study. 3D\u2010\n STE<\/jats:styled-content>\n was performed and global longitudinal strain (\n GLS<\/jats:styled-content>\n ), global circumferential strain (\n GCS<\/jats:styled-content>\n ), global radial strain (\n GRS<\/jats:styled-content>\n ), and global area strain (\n GAS<\/jats:styled-content>\n ) were measured before coronary angiography. A Gensini score of \u226520 was accepted as critical\n CAD<\/jats:styled-content>\n . Correlation between Gensini scores and 3D\u2010\n STE<\/jats:styled-content>\n results were evaluated.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Mean age was 60.7\u00a0\u00b1\u00a010.01\u00a0years, and 55% of the patient population were male. There were not any significant differences between critical\n CAD<\/jats:styled-content>\n and noncritical\n CAD<\/jats:styled-content>\n groups for age, gender, history of hypertension, diabetes mellitus, hyperlipidemia, and Left Ventricular Ejection Fraction. Mean\n GLS<\/jats:styled-content>\n was \u221212,\n GCS<\/jats:styled-content>\n was \u221218.8,\n GRS<\/jats:styled-content>\n was 33.4,\n GAS<\/jats:styled-content>\n was \u221228.9, and mean Gensini score was 18.8.\n GLS<\/jats:styled-content>\n and all other strain parameters were significantly worse in patients with critical\n CAD<\/jats:styled-content>\n group compared with noncritical\n CAD<\/jats:styled-content>\n group and also positive linear correlation was observed between Gensini score and all measured strain parameters (\n r<\/jats:italic>\n \u00a0=\u00a00.568,\n P<\/jats:italic>\n \u00a0<\u00a00.001 for Gensini score and\n GLS<\/jats:styled-content>\n ;\n r<\/jats:italic>\n \u00a0=\u00a00.617,\n P<\/jats:italic>\n \u00a0<\u00a00.001 for Gensini score and\n GAS<\/jats:styled-content>\n ). A\n GLS<\/jats:styled-content>\n value of >\u221210 has 88.9% sensitivity and 92.9% specificity; A\n GAS<\/jats:styled-content>\n value of >\u221221 has 97.2% sensitivity and 88.1% specificity to detect critical\n CAD<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n 3D\u2010\n STE<\/jats:styled-content>\n is a noninvasive and handy parameter to detect subclinical left ventricular dysfunction and global strain values were significantly correlated with\n CAD<\/jats:styled-content>\n severity.\n GAS<\/jats:styled-content>\n has the sensitivity of 97.2% and specificity of 88.1% to detect critical\n CAD<\/jats:styled-content>\n . Adding 3D strain echocardiography to exercise test or myocardial perfusion scintigraphy might increase sensitivity to detect critical\n CAD<\/jats:styled-content>\n in clinical practice.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/echo.14214","type":"journal-article","created":{"date-parts":[[2018,12,5]],"date-time":"2018-12-05T01:05:06Z","timestamp":1543971906000},"page":"320-327","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["3D\u2010speckle tracking echocardiography for assessment of coronary artery disease severity in stable angina pectoris"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3895-1923","authenticated-orcid":false,"given":"Mustafa","family":"Dogdus","sequence":"first","affiliation":[{"name":"Department of Cardiology Ege University School of Medicine Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evrim","family":"Simsek","sequence":"additional","affiliation":[{"name":"Department of Cardiology Ege University School of Medicine Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cahide Soydas","family":"Cinar","sequence":"additional","affiliation":[{"name":"Department of Cardiology Ege University School of Medicine Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8183.1994.tb00448.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-017-0367-1"},{"key":"e_1_2_8_4_1","unstructured":"Health Quality Ontario: Stress echocardiography for the diagnosis of coronary artery disease: an evidence\u2010based analysis. 10th ed.2010."},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.110.959817"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2008.06.091"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.12115"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2013.07.018"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jes026"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(83)80105-2"},{"issue":"6","key":"e_1_2_8_11_1","first-page":"514","article-title":"Assessment of the association between the personality traits of young patients with acute coronary syndrome and the severity of coronary artery disease","volume":"45","author":"Bayar N","year":"2017","journal-title":"Turk Kardiyol Dern Ars"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00019501-200002000-00013"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.5603\/KP.a2014.0208"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.13764"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2012.01773.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jet103"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2010.08.011"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-017-1147-6"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.13806"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12947-018-0144-9"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.112.000627"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecho.14214","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.14214","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/echo.14214","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.14214","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T09:36:30Z","timestamp":1694684190000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.14214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,4]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["10.1111\/echo.14214"],"URL":"https:\/\/doi.org\/10.1111\/echo.14214","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,4]]},"assertion":[{"value":"2018-09-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}