{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:25:10Z","timestamp":1740137110563,"version":"3.37.3"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,1,28]],"date-time":"2019-01-28T00:00:00Z","timestamp":1548633600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To identify left ventricular (<jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content>) dyssynchrony and associated factors in atrial septal defect (<jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>) patients, using real time three\u2010dimensional echocardiogram (<jats:styled-content style=\"fixed-case\">RT<\/jats:styled-content>3<jats:styled-content style=\"fixed-case\">DE<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Left ventricular dysfunction has been observed in <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>. Few studies have utilized <jats:styled-content style=\"fixed-case\">RT<\/jats:styled-content>3<jats:styled-content style=\"fixed-case\">DE<\/jats:styled-content> to assess <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> wall\u2010motion abnormality in <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients aged \u22651\u00a0year with <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>, with or without partial anomalous pulmonary venous drainage (<jats:styled-content style=\"fixed-case\">PAPVD<\/jats:styled-content>), were included over 1\u00a0year. Additional cardiac defects or abnormalities independently affecting <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> function were excluded. 2<jats:styled-content style=\"fixed-case\">DE<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">RT<\/jats:styled-content>3<jats:styled-content style=\"fixed-case\">DE<\/jats:styled-content>\u2010derived <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> function data were recorded. Student's <jats:italic>t<\/jats:italic> test and Pearson's correlation were used for analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 104 patients (69 females) aged 1\u201357\u00a0years, ostium secundum <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content> was present in 97 and sinus venosus <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content> in 7. Maximum excursion increased significantly with age, weight, and body surface area (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Majority of children (58%) aged 3\u20135\u00a0years showed no delay in segmental excursion. Lateral wall excursional delay was greater beyond 5\u00a0years or with weight\u00a0&gt;\u00a015\u00a0kg (42% as compared to 20% in &lt;15\u00a0kg). In patients weighing\u00a0&lt;\u00a015\u00a0kg, time to minimum systolic volume (Tmsv 16\u2010<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>) was higher with <jats:styled-content style=\"fixed-case\">PAPVD<\/jats:styled-content> and with indexed defect size\u00a0&gt;\u00a040\u00a0mm\/m<jats:sup>2<\/jats:sup>, though not statistically significant. As compared to <jats:styled-content style=\"fixed-case\">EF<\/jats:styled-content> estimation by 2<jats:styled-content style=\"fixed-case\">DE<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> EF<\/jats:styled-content> derived using <jats:styled-content style=\"fixed-case\">RT<\/jats:styled-content>3<jats:styled-content style=\"fixed-case\">DE<\/jats:styled-content> was significantly lower (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Left ventricular dyssynchrony is least between 3 and 5\u00a0years. Beyond 5\u00a0years, delayed lateral wall excursion is seen. With an indexed defect size exceeding 40\u00a0mm\/m<jats:sup>2<\/jats:sup>, and in the presence of <jats:styled-content style=\"fixed-case\">PAPVD<\/jats:styled-content>, time to minimum systolic volume is higher.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.14269","type":"journal-article","created":{"date-parts":[[2019,1,29]],"date-time":"2019-01-29T07:59:35Z","timestamp":1548748775000},"page":"577-584","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The left ventricle in atrial septal defect: Looking through 3D glasses"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7797-0801","authenticated-orcid":false,"given":"Sweta","family":"Mohanty","sequence":"first","affiliation":[{"name":"Aster CMI Hospital  Bengaluru India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angel","family":"Solomon","sequence":"additional","affiliation":[{"name":"Aster CMI Hospital  Bengaluru India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,1,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.13757"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.4172\/2368-0512.1000018"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2011.07.003"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.065607"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(88)92606-X"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/147323000403200102"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2004.058388"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.70.4.657"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2007.01056.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2004.10.007"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.82.3.300"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.4070\/kcj.2011.41.11.633"},{"key":"e_1_2_7_14_1","first-page":"161","volume-title":"Pediatric Cardiology for Practitioners","author":"Park MK","year":"2007"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(91)90474-V"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV12SXA3"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00058-2"},{"key":"e_1_2_7_18_1","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/B978-1-4160-2390-6.50039-8","volume-title":"Nadas' Pediatric Cardiology","author":"Keane JF","year":"2006"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.13267"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.08.026"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecho.14269","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.14269","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T04:04:46Z","timestamp":1694491486000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.14269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,28]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.1111\/echo.14269"],"URL":"https:\/\/doi.org\/10.1111\/echo.14269","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"type":"print","value":"0742-2822"},{"type":"electronic","value":"1540-8175"}],"subject":[],"published":{"date-parts":[[2019,1,28]]},"assertion":[{"value":"2018-10-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}