{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:00:11Z","timestamp":1747184411647,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,3,22]],"date-time":"2019-03-22T00:00:00Z","timestamp":1553212800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2019,4]]},"abstract":"Background<\/jats:title>Left bundle branch block (LBBB<\/jats:styled-content>) is associated with a high risk of death, particularly from ventricular tachyarrhythmia and myocardial infarction. It is difficult to clinically differentiate between ischemic and nonischemic LBBB<\/jats:styled-content>. In this study, we investigated whether advanced echocardiographic variables, such as strain delay index (SDI<\/jats:styled-content>) and postsystolic index (PSI<\/jats:styled-content>), can be used to distinguish coronary artery disease (CAD<\/jats:styled-content>) in patients with LBBB<\/jats:styled-content>.<\/jats:p><\/jats:sec>Methods<\/jats:title>Our study included 102 patients with LBBB<\/jats:styled-content>. All patients underwent echocardiography. The left ventricular ejection fraction (LVEF<\/jats:styled-content>), left ventricular mass, PSI<\/jats:styled-content>, SDI<\/jats:styled-content>, global longitudinal strain (GLS<\/jats:styled-content>), and time\u2010to\u2010peak longitudinal strain were then calculated. Coronary angiography was performed, and the patients were divided into groups with significant CAD<\/jats:styled-content> and without significant CAD<\/jats:styled-content>.<\/jats:p><\/jats:sec>Results<\/jats:title>Patients in the group with significant CAD<\/jats:styled-content> were older than the patients in the group without significant CAD<\/jats:styled-content>. The group had a higher prevalence of diabetes mellitus, hypertension, hyperlipidemia, and family history of CAD<\/jats:styled-content> than the group without significant CAD<\/jats:styled-content>. The group with significant CAD<\/jats:styled-content> also had lower LVEF<\/jats:styled-content> and GLS<\/jats:styled-content> than the group without significant CAD<\/jats:styled-content>. The group without significant CAD<\/jats:styled-content> showed a direct correlation between LVEF<\/jats:styled-content> and SDI<\/jats:styled-content> and an inverse correlation between LVEF<\/jats:styled-content> and PSI<\/jats:styled-content>: P<\/jats:italic> value\u00a0=\u00a00.040 and r<\/jats:italic>\u00a0=\u00a00.255, and P<\/jats:italic> value\u00a0=\u00a00.001 and r<\/jats:italic>\u00a0=\u00a0\u22120.427, respectively. However, the group with significant CAD<\/jats:styled-content> did not show any significant correlation between LVEF<\/jats:styled-content> and SDI<\/jats:styled-content> or PSI<\/jats:styled-content>.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Strain delay index and PSI<\/jats:styled-content> may be useful markers in distinguishing CAD<\/jats:styled-content> in patients with LBBB<\/jats:styled-content> and preserved LVEF<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.14313","type":"journal-article","created":{"date-parts":[[2019,3,22]],"date-time":"2019-03-22T13:56:39Z","timestamp":1553262999000},"page":"687-695","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Postsystolic index for distinguishing coronary artery disease in left bundle branch block"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2700-4074","authenticated-orcid":false,"given":"Maryam","family":"Nabati","sequence":"first","affiliation":[{"name":"Department of Cardiology Faculty of Medicine Cardiovascular Research Center Mazandaran University of Medical Sciences Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Payam","family":"Mahmoudi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Cardiovascular Research Center Mazandaran University of Medical Sciences Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamshid","family":"Yazdani","sequence":"additional","affiliation":[{"name":"Department of Biostatics Faculty of Health Mazandaran University of Medical Sciences Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Homa","family":"Parsaee","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Cardiovascular Research Center Iran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,3,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.5603\/CJ.a2015.0005"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2008.05.070"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.accreview.2004.02.026"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfr073"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.117.008367"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.62.2.240"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.19.2560"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc08-S055"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.549857"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2003.06.010"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euje.2005.12.014"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.4068\/cmj.2016.52.2.101"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-7317(03)00335-3"},{"issue":"2","key":"e_1_2_7_15_1","first-page":"48","article-title":"Guidelines for the echocardiography assessment of the right heart in adults: a report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography","volume":"43","author":"Daskalov I","year":"2012","journal-title":"S'rdechno\u2010s\u2019 dovi Zabolyavaniya"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq213"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(78)90981-5"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1071-3581(97)90103-3"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.4236\/wjcd.2013.32034"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.113.120063"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1999.2008"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jep097"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.13022"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e32834f6b2b"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euje.2006.07.006"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.14313","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/echo.14313","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.14313","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T12:05:37Z","timestamp":1694347537000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.14313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,22]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["10.1111\/echo.14313"],"URL":"https:\/\/doi.org\/10.1111\/echo.14313","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"type":"print","value":"0742-2822"},{"type":"electronic","value":"1540-8175"}],"subject":[],"published":{"date-parts":[[2019,3,22]]},"assertion":[{"value":"2018-11-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}