{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:00:12Z","timestamp":1747184412202,"version":"3.40.5"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,3,25]],"date-time":"2019-03-25T00:00:00Z","timestamp":1553472000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Our aim was to test the hypothesis that comprehensive simplified left atrial (<jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>) assessment derived from routine echocardiography may be more useful than assessment of <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> volume alone for predicting atrial fibrillation (<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>) recurrence after pulmonary vein isolation (<jats:styled-content style=\"fixed-case\">PVI<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We studied 156 patients with paroxysmal <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content>) who had undergone <jats:styled-content style=\"fixed-case\">PVI<\/jats:styled-content>. Echocardiography was performed within two days before <jats:styled-content style=\"fixed-case\">PVI<\/jats:styled-content>. Maximum (Max\u2010<jats:styled-content style=\"fixed-case\">LAV<\/jats:styled-content>i) and minimum <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> volume index (Min\u2010<jats:styled-content style=\"fixed-case\">LAV<\/jats:styled-content>i) were calculated with the biplane modified Simpson's method, and then normalized to the body surface area. On the basis of previous findings, the predefined cutoff value of Max\u2010<jats:styled-content style=\"fixed-case\">LAV<\/jats:styled-content>i for <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> recurrence was set at Max\u2010<jats:styled-content style=\"fixed-case\">LAV<\/jats:styled-content>i\u00a0\u2265\u00a034\u00a0mL\/m<jats:sup>2<\/jats:sup>. \u0394<jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> volume index (\u0394<jats:styled-content style=\"fixed-case\">LAV<\/jats:styled-content>i) was also calculated as Max\u2010<jats:styled-content style=\"fixed-case\">LAV<\/jats:styled-content>i minus Min\u2010<jats:styled-content style=\"fixed-case\">LAV<\/jats:styled-content>i. The follow\u2010up period after <jats:styled-content style=\"fixed-case\">PVI<\/jats:styled-content> was 24\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> recurrence was observed in 35 patients. Multivariate logistic regression analysis showed that \u0394<jats:styled-content style=\"fixed-case\">LAV<\/jats:styled-content>i (odds ratio [<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>]: 1.131; 95% confidence interval [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>]: 1.057\u20101.221; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) was an independent predictor of <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> recurrence. Sequential logistic regression models for predicting <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> recurrence revealed that a model based on clinical variables including age, gender and <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> duration (<jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a01.65) was improved by the addition of Max\u2010<jats:styled-content style=\"fixed-case\">LAV<\/jats:styled-content>i\u00a0\u2265\u00a034\u00a0mL\/m<jats:sup>2<\/jats:sup> (<jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a013.8; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), and further improved by the addition of \u0394<jats:styled-content style=\"fixed-case\">LAV<\/jats:styled-content>i (<jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a018.2; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.036). Of note is that only 1.02\u00a0\u00b1\u00a00.10\u00a0minutes per patient was needed to obtain a comprehensive <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> assessment that included Max\u2010<jats:styled-content style=\"fixed-case\">LAV<\/jats:styled-content>i, Min\u2010<jats:styled-content style=\"fixed-case\">LAV<\/jats:styled-content>i, and \u0394<jats:styled-content style=\"fixed-case\">LAV<\/jats:styled-content>i.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This easy\u2010to\u2010use comprehensive simplified <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> approach from routine echocardiography may well have clinical implications for better management of <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content> patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.14315","type":"journal-article","created":{"date-parts":[[2019,3,25]],"date-time":"2019-03-25T19:29:55Z","timestamp":1553542195000},"page":"862-869","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Combined assessment of left atrial volume parameters for predicting recurrence of atrial fibrillation following pulmonary vein isolation in patients with paroxysmal atrial fibrillation"],"prefix":"10.1111","volume":"36","author":[{"given":"Fumitaka","family":"Soga","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Division of Cardiovascular Medicine Kobe University Graduate School of Medicine  Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1642-7039","authenticated-orcid":false,"given":"Hidekazu","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Internal 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