{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T18:21:02Z","timestamp":1758824462788,"version":"3.40.5"},"reference-count":7,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,4,22]],"date-time":"2019-04-22T00:00:00Z","timestamp":1555891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To report the usefulness of harmonic imaging in echocardiography to visualize and direct the implantation of the Medtronic micro vascular plug (<jats:styled-content style=\"fixed-case\">MVP<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Off label use of the <jats:styled-content style=\"fixed-case\">MVP<\/jats:styled-content> was reported for transcatheter occlusion of patent ductus arteriosus (<jats:styled-content style=\"fixed-case\">PDA<\/jats:styled-content>) in premature infants. The device is poorly visible on fluoroscopy and echocardiography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In 9 consecutive premature infants, the <jats:styled-content style=\"fixed-case\">MVP<\/jats:styled-content> was used for transcatheter closure of the <jats:styled-content style=\"fixed-case\">PDA<\/jats:styled-content>. In each, the ability of conventional echocardiographic imaging was compared to harmonic imaging, and the device was deployed in the <jats:styled-content style=\"fixed-case\">PDA<\/jats:styled-content> using echocardiography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In each subject, harmonic imaging proved superior to conventional echocardiography to visualize the <jats:styled-content style=\"fixed-case\">MVP<\/jats:styled-content> in premature infants using 12 and 8\u00a0MHz probes. Once the delivery, catheter was across the <jats:styled-content style=\"fixed-case\">PDA<\/jats:styled-content> into the descending aorta, and the <jats:styled-content style=\"fixed-case\">MVP<\/jats:styled-content> advanced to the catheter tip, positioning, and deployment of the device was possible without fluoroscopy. All devices were deployed appropriately with immediate occlusion and no obstruction to the left pulmonary artery or aorta.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">MVP<\/jats:styled-content> can be accurately imaged using harmonic imaging, even in the near field in premature infants. Precise implantation of the <jats:styled-content style=\"fixed-case\">MVP<\/jats:styled-content> in the <jats:styled-content style=\"fixed-case\">PDA<\/jats:styled-content> of premature infants is possible with echocardiographic imaging of the device and vascular structures.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.14335","type":"journal-article","created":{"date-parts":[[2019,4,22]],"date-time":"2019-04-22T07:01:40Z","timestamp":1555916500000},"page":"944-947","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Echocardiographic imaging of the Medtronic Micro Vascular Plug<sup>\u2122<\/sup> during off label placement in the premature infant with patent ductus arteriosus"],"prefix":"10.1111","volume":"36","author":[{"given":"James M.","family":"Berry","sequence":"first","affiliation":[{"name":"Masonic Children's Hospital University of Minnesota  Minneapolis Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gurumurthy","family":"Hiremath","sequence":"additional","affiliation":[{"name":"Masonic Children's Hospital University of Minnesota  Minneapolis Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"Heal","sequence":"additional","affiliation":[{"name":"Masonic Children's Hospital University of Minnesota  Minneapolis Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5809-5557","authenticated-orcid":false,"given":"John L.","family":"Bass","sequence":"additional","affiliation":[{"name":"Masonic Children's Hospital University of Minnesota  Minneapolis Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,4,22]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_6_2_1","DOI":"10.1136\/adc.2005.078600"},{"doi-asserted-by":"publisher","key":"e_1_2_6_3_1","DOI":"10.1002\/ccd.22931"},{"doi-asserted-by":"publisher","key":"e_1_2_6_4_1","DOI":"10.1002\/ccd.27091"},{"doi-asserted-by":"publisher","key":"e_1_2_6_5_1","DOI":"10.1002\/ccd.25534"},{"doi-asserted-by":"publisher","key":"e_1_2_6_6_1","DOI":"10.1002\/ccd.26878"},{"doi-asserted-by":"publisher","key":"e_1_2_6_7_1","DOI":"10.1002\/ccd.26855"},{"doi-asserted-by":"publisher","key":"e_1_2_6_8_1","DOI":"10.1016\/S0894-7317(98)70055-0"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.14335","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/echo.14335","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.14335","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T11:52:40Z","timestamp":1694346760000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.14335"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,22]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1111\/echo.14335"],"URL":"https:\/\/doi.org\/10.1111\/echo.14335","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"type":"print","value":"0742-2822"},{"type":"electronic","value":"1540-8175"}],"subject":[],"published":{"date-parts":[[2019,4,22]]},"assertion":[{"value":"2019-01-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}