{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T02:29:52Z","timestamp":1784687392815,"version":"3.55.0"},"reference-count":28,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T00:00:00Z","timestamp":1562025600000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Dobutamine stress echocardiography (<jats:styled-content style=\"fixed-case\">DSE<\/jats:styled-content>) is an important tool in the diagnosis of coronary artery disease. However, there is hesitation in clinical practice for using it in patients with Chagas disease (<jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>) due to the arrhythmogenic potential of this heart condition. This study aimed to evaluate the incidence and variables associated with arrhythmias during <jats:styled-content style=\"fixed-case\">DSE<\/jats:styled-content> in a population of patients with <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A population of 205 consecutive patients with <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> and suspected coronary heart disease was assessed through a retrospective database analysis. <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> was confirmed in all patients by serological testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age of the patients selected was 64\u00a0years, and 65.4% of the patients were female. Significant arrhythmias occurred as follows: nonsustained ventricular tachycardia in 7.3% of patients; supraventricular tachycardia and sustained ventricular tachycardia in 1%; and atrial fibrillation in 0.5%. Nonsignificant arrhythmias occurred as follows: premature ventricular contractions in 48% of patients and bigeminy in 4.4%. Values for the wall\u2010motion score index at rest greater than 1.12 and 1.18 were independently correlated with the occurrence of nonsignificant arrhythmias (odds ratio [<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>]\u00a0=\u00a02.90, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and significant arrhythmias (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a04.23, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.044), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">DSE<\/jats:styled-content> should be considered a safe examination in patients with <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> despite the known increased risk of arrhythmias in this group of patients. The occurrence of arrhythmias was low in this study. Abnormal wall\u2010motion score index values at rest were associated with the occurrence of significant and nonsignificant arrhythmias during the test.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.14341","type":"journal-article","created":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T12:27:09Z","timestamp":1562070429000},"page":"1338-1345","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Incidence and variables associated with arrhythmias during dobutamine\u2013atropine stress echocardiography among patients with Chagas disease"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9131-0439","authenticated-orcid":false,"given":"Daniela","family":"Carmo Rassi","sequence":"first","affiliation":[{"name":"Faculdade de Medicina da Universidade Federal de Goi\u00e1s  Goi\u00e2nia GO Brazil"},{"name":"CDI \u2010 Centro de Diagn\u00f3stico por Imagem  Goi\u00e2nia GO 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