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However, deciding the optimal surgical timing can be very difficult, since the line between the absence of symptoms and being minimally symptomatic, especially in the elderly, is blurred. Another relevant issue regards the second surgical criterion: operating on a patient with a reduced left ventricular ejection fraction or with a dilated left ventricle might jeopardize the possibility of a fully reverse remodeling of the heart after surgery. In this scenario, the left atrium might play an important role. In particular, left atrial deformation might be a very useful tool to detect early ultrastructural alterations, and help or support guiding a patient\u2010tailored treatment at an early stage, optimizing the outcome in the long term.<\/jats:p>","DOI":"10.1111\/echo.14426","type":"journal-article","created":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T13:36:32Z","timestamp":1561988192000},"page":"1559-1565","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The role of the left atrial function in the surgical management of aortic and mitral valve disease"],"prefix":"10.1111","volume":"36","author":[{"given":"Matteo","family":"Cameli","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Disease University of Siena Siena 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