{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T23:26:50Z","timestamp":1784849210466,"version":"3.55.0"},"reference-count":27,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,8,5]],"date-time":"2019-08-05T00:00:00Z","timestamp":1564963200000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Speckle tracking echocardiography (STE) is a validated method to measure\u00a0longitudinal deformation in premature infants, but there is a paucity of data on STE\u2010derived circumferential and radial strain in this population. We assessed the feasibility and reproducibility of circumferential and radial deformation measurements in premature infants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a prospective study of 40 premature infants (&lt;29\u00a0weeks of gestation at birth), STE\u2010derived circumferential and radial strain, systolic strain rate (SRs), early diastolic strain rate (SRe), and late diastolic strain rate (SRa) were measured on day 2 and day 8. Intra\u2010 and inter\u2010observer reproducibility analysis were performed using Bland\u2013Altman analysis, coefficient of variation (COV), and intra\u2010class correlation coefficient (ICC). The impact of a persistent patent ductus arteriosus (PDA) was analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Deformation analysis was feasible in 98% of the acquisitions. Circumferential parameters demonstrated excellent intra\u2010 and inter\u2010observer reproducibility with an ICC between 0.89 and 0.99 (all <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and a COV between 4% and 13%. Radial parameters demonstrated acceptable intra\u2010 and inter\u2010observer reproducibility with an ICC between 0.73 and 0.96 (all <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and a COV between 14% and 27%. Infants with a PDA on day 8 (n\u00a0=\u00a021, 53%) demonstrated higher radial strain, SRs and SRe. There were no differences in circumferential parameters with a PDA at either time point.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study demonstrates clinical feasibility and reproducibility of circumferential and radial strain by STE in premature infants. A PDA elevates radial deformation measures, suggesting that the increased LV preload from a PDA may augment intrinsic contractility in the radial but not circumferential plane.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.14442","type":"journal-article","created":{"date-parts":[[2019,8,6]],"date-time":"2019-08-06T06:32:54Z","timestamp":1565073174000},"page":"1532-1539","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Circumferential and radial deformation assessment in premature infants: Ready for primetime?"],"prefix":"10.1111","volume":"36","author":[{"given":"Neidin","family":"Bussmann","sequence":"first","affiliation":[{"name":"Department of Neonatology The Rotunda Hospital Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4778-3888","authenticated-orcid":false,"given":"Aisling","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Neonatology The Rotunda Hospital Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessia","family":"Cappelleri","sequence":"additional","affiliation":[{"name":"Department of Neonatology The Rotunda Hospital Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip T.","family":"Levy","sequence":"additional","affiliation":[{"name":"Division of Newborn Medicine Boston Children's Hospital Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naomi","family":"McCallion","sequence":"additional","affiliation":[{"name":"Department of Neonatology The Rotunda Hospital Dublin Ireland"},{"name":"Department of Paediatrics School of Medicine Royal College of Surgeons in Ireland Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orla","family":"Franklin","sequence":"additional","affiliation":[{"name":"Department of Paediatric Cardiology Our Lady's Children's Hospital Crumlin Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2933-822X","authenticated-orcid":false,"given":"Afif","family":"EL\u2010Khuffash","sequence":"additional","affiliation":[{"name":"Department of Neonatology The Rotunda Hospital Dublin Ireland"},{"name":"Department of Paediatrics School of Medicine Royal College of Surgeons in Ireland Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,8,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41390-018-0080-2"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41390-019-0293-z"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2019.02.004"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.45.3.248"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.24.3.339"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.754424"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2010.02.015"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2013.06.005"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2014.03.006"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2017.03.003"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2011.09.016"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951116002687"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2013.03.006"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2013.08.019"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2010.09.018"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2015.09.028"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41390-018-0076-y"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1159\/000337329"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4780060404"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2010.08.010"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2014.10.017"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.12716"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.13919"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12947-017-0111-x"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2006.11.003"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2015.11.016"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2014.11.003"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.14442","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/echo.14442","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.14442","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T11:34:46Z","timestamp":1694259286000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.14442"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":27,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["10.1111\/echo.14442"],"URL":"https:\/\/doi.org\/10.1111\/echo.14442","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8]]},"assertion":[{"value":"2019-05-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}