{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:21:19Z","timestamp":1787163679021,"version":"build-2736575974"},"reference-count":22,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,8,26]],"date-time":"2019-08-26T00:00:00Z","timestamp":1566777600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2019,9]]},"abstract":"Abstract<\/jats:title>\n \n Objectives<\/jats:title>\n \n The aim was to evaluate the role of tissue Doppler imaging (\n TDI<\/jats:styled-content>\n ) and speckle tracking echocardiography (\n STE<\/jats:styled-content>\n ), to identify myocardial dysfunction, and to evaluate myocardial segmental deformation in acute viral myocarditis.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Twenty\u2010one patients and twelve healthy children were studied prospectively. The\n TDI<\/jats:styled-content>\n and\n STE<\/jats:styled-content>\n were performed before and after treatment. The myocardial velocities (S\n m<\/jats:sub>\n , E\n m<\/jats:sub>\n , and A\n m<\/jats:sub>\n ) and time intervals (isovolumic contraction, isovolumic relaxation, and ejection times [\n ET<\/jats:styled-content>\n ]) at interventricular septum (\n IVS<\/jats:styled-content>\n ), left, and right ventricular basal segments were examined by\n TDI<\/jats:styled-content>\n . The left ventricular global longitudinal strain (\n LVGLS<\/jats:styled-content>\n ) and strain rate (\n LVGLSR<\/jats:styled-content>\n ), left ventricular global circumferential strain (\n LVGCS<\/jats:styled-content>\n ) and strain rate (\n LVGCSR<\/jats:styled-content>\n ), and right ventricular global longitudinal strain (\n RVGLS<\/jats:styled-content>\n ) and strain rate (\n RVGLSR<\/jats:styled-content>\n ) were examined by\n STE<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n S\n m<\/jats:sub>\n and E\n m<\/jats:sub>\n at\n IVS<\/jats:styled-content>\n and at\n LV<\/jats:styled-content>\n ,\n ET<\/jats:styled-content>\n at\n IVS<\/jats:styled-content>\n ,\n ET<\/jats:styled-content>\n at\n RV<\/jats:styled-content>\n ,\n ET<\/jats:styled-content>\n at\n LV<\/jats:styled-content>\n were significantly lower in patients before treatment than controls.\n LVGLS<\/jats:styled-content>\n ,\n LVGLSR<\/jats:styled-content>\n ,\n LVGCS<\/jats:styled-content>\n ,\n LVGCSR<\/jats:styled-content>\n ,\n RVGLS<\/jats:styled-content>\n ,\n RVGLSR<\/jats:styled-content>\n were significantly decreased in patients before treatment than controls. There was significant improvement for\n LVGLS<\/jats:styled-content>\n ,\n LVGLSR<\/jats:styled-content>\n ,\n LVGCS<\/jats:styled-content>\n ,\n LVGCSR<\/jats:styled-content>\n , and\n RVGLS<\/jats:styled-content>\n in patients after treatment. S\n m<\/jats:sub>\n , E\n m<\/jats:sub>\n , and A\n m<\/jats:sub>\n at\n LV<\/jats:styled-content>\n were significantly lower in patients before treatment than in patients after treatment. In spite of improvements, S\n m<\/jats:sub>\n , E\n m<\/jats:sub>\n , and\n ET<\/jats:styled-content>\n at\n IVS<\/jats:styled-content>\n ,\n LVGLS<\/jats:styled-content>\n ,\n LVGLSR<\/jats:styled-content>\n ,\n LVGCS<\/jats:styled-content>\n ,\n LVGCSR<\/jats:styled-content>\n were significantly lower in patients after treatment than controls.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n The\n TDI<\/jats:styled-content>\n and\n STE<\/jats:styled-content>\n were useful methods for detection of early myocardial dysfunction and evaluation of treatment outcomes in acute viral myocarditis.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/echo.14449","type":"journal-article","created":{"date-parts":[[2019,8,27]],"date-time":"2019-08-27T02:45:23Z","timestamp":1566873923000},"page":"1666-1674","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["The assessment of treatment outcomes in patients with acute viral myocarditis by speckle tracking and tissue Doppler methods"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0707-2678","authenticated-orcid":false,"given":"Haz\u0131m Alper","family":"Gursu","sequence":"first","affiliation":[{"name":"Department of Pediatric Cardiology Ankara Child Health and Diseases Hematology Oncology Training and Research Hospital University of Health Sciences Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim Ilker","family":"Cetin","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Ankara Child Health and Diseases Hematology Oncology Training and Research Hospital University of Health Sciences Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2466-3285","authenticated-orcid":false,"given":"Emine","family":"Azak","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Ankara Child Health and Diseases Hematology Oncology Training and Research Hospital University of Health Sciences Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayse Esin","family":"Kibar","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Ankara Child Health and Diseases Hematology Oncology Training and Research Hospital University of Health Sciences Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Surucu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Ankara Child Health and Diseases Hematology Oncology Training and Research Hospital University of Health Sciences Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Orgun","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Ankara Child Health and Diseases Hematology Oncology Training and Research Hospital University of Health Sciences Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Utku","family":"Pamuk","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Ankara Child Health and Diseases Hematology Oncology Training and Research Hospital University of Health Sciences Ankara 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