{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T04:56:13Z","timestamp":1778820973554,"version":"3.51.4"},"reference-count":45,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T00:00:00Z","timestamp":1566518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Preterm births and respiratory distress syndrome (RDS) are associated with pulmonary vascular disease and altered myocardial function. We serially assessed up to 1\u00a0year of age the effects of RDS on global and regional myocardial function of preterm infants, compared to preterm and term controls using conventional echocardiography parameters, tissue Doppler velocities and deformation analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>A total of 120 infants (30 preterm [PT] with RDS, 30 PT controls without RDS, and 60 term controls) underwent conventional and tissue Doppler echocardiography within 72\u00a0hours of birth, at corrected term age for the preterm infants, at 1\u00a0month corrected, and at 1\u00a0year corrected age. At birth, compared to preterm and term controls, the PT\u2010RDS group had decreased right ventricular (RV) long\u2010axis function, systolic velocity, peak systolic strain, shorter pulmonary arterial acceleration time (PAAT), and lower ratio of PAAT to RV ejection time (PAAT:RVET). Preterm infants had left ventricular (LV) diastolic dysfunction at birth (lower early diastolic myocardial velocity, mitral E velocity, and mitral E:A ratio), and reduced long\u2010axis systolic velocities and shortening. Differences between groups disappeared by 1\u00a0month corrected age, except PAAT:RVET which remained lower in the PT\u2010RDS group. At 1\u00a0year, RV function was normal in PT\u2010RDS apart from systolic strain rate, and LV function was normal apart from lower stroke volume and shortening, relative to body weight.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>PT\u2010RDS had lower left and right ventricular systolic and diastolic function at birth which improved over time, suggesting postnatal maturation of cardiac function and resolution of lung disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.14462","type":"journal-article","created":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T11:57:29Z","timestamp":1566561449000},"page":"1713-1726","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Longitudinal evaluation of myocardial function in preterm infants with respiratory distress syndrome"],"prefix":"10.1111","volume":"36","author":[{"given":"Chuen 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