{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T01:05:31Z","timestamp":1786323931741,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,10,14]],"date-time":"2019-10-14T00:00:00Z","timestamp":1571011200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Right ventricular (RV) function is an important factor in the prognosis of chronic thromboembolic pulmonary hypertension (CTEPH) in patients. In our study, we aimed to evaluate the timing and magnitude of regional RV function before and after balloon pulmonary angioplasty (BPA) using speckle tracking echocardiography (STE) and their relation to clinical and hemodynamic parameters in patients with CTEPH.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Method<\/jats:title><jats:p>We enrolled 20 CTEPH patients and 19 healthy subjects in our study. Enrolled patients underwent echocardiography, right heart catheterization (RHC), and 6\u2010minute walk distance (6MWD) test at baseline and after the BPA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In hemodynamic RHC measurements and clinical evaluations, mean pulmonary artery pressure (median: 53.5\u00a0mm\u00a0Hg vs 37.0\u00a0mm\u00a0Hg, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.001) and pulmonary vascular resistance (median: 12 Wood units [WU] vs 7\u00a0WU, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.001) and pro\u2010brain natriuretic peptide level decreased and 6MWD increased after BPA sessions. There was no statistically significant difference between before and after the BPA sessions in conventional echocardiographic measurements. In STE analysis, the electromechanical delay (EMD) between RV free wall (RVF) and LV lateral wall (LVL) (median: 65\u00a0ms vs 47.5\u00a0ms, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.01) and RV peak systolic strain dispersion index (52\u00a0ms vs 29\u00a0ms, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.001) were higher in patients with CTEPH than healthy controls before the BPA. Both these parameters decreased significantly after BPA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Chronic thromboembolic pulmonary hypertension was associated with RV electromechanical delay and dispersion based on the STE analysis. Balloon pulmonary angioplasty might have an important impact on the improvement of both RV function and hemodynamics.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.14503","type":"journal-article","created":{"date-parts":[[2019,10,14]],"date-time":"2019-10-14T09:54:33Z","timestamp":1571046873000},"page":"2050-2056","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Improvements of right ventricular function and hemodynamics after balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5156-0302","authenticated-orcid":false,"given":"Batur Gonenc","family":"Kanar","sequence":"first","affiliation":[{"name":"Department of Cardiology Faculty of Medicine Marmara University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00fclent","family":"Mutlu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Faculty of Medicine Marmara University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halil","family":"Atas","sequence":"additional","affiliation":[{"name":"Department of Cardiology Faculty of Medicine Marmara University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dursun","family":"Akaslan","sequence":"additional","affiliation":[{"name":"Department of Cardiology Faculty of Medicine Marmara University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bedrettin","family":"Y\u0131ld\u0131zeli","sequence":"additional","affiliation":[{"name":"Department of Chest Medicine Surgery Faculty of Medicine Marmara University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,10,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1183\/09059180.00009211"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hfc.2018.02.009"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-018-2012-2"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1183\/16000617.0111-2016"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2009.01.017"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1651481"},{"key":"e_1_2_6_8_1","first-page":"1127","article-title":"2015 ESC\/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension","volume":"73","author":"Gali\u00e8 N","year":"2015","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jev014"},{"key":"e_1_2_6_10_1","first-page":"135","article-title":"Physiological basis in the assessment of myocardial mechanics using speckle\u2010tracking echocardiography 2D. 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