{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T20:23:33Z","timestamp":1780604613374,"version":"3.54.1"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,1,24]],"date-time":"2020-01-24T00:00:00Z","timestamp":1579824000000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["No. 81000615"],"award-info":[{"award-number":["No. 81000615"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["No.81530056"],"award-info":[{"award-number":["No.81530056"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Research clinician program of Tongji Medical College of Huazhong University of Science and Technology","award":["No. 5001530051"],"award-info":[{"award-number":["No. 5001530051"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To identify the risk factors causing misdiagnosis by echocardiography and missed diagnosis of anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Echocardiographic results of 16 patients with ALCAPA confirmed by surgery in Union Hospital, Wuhan, were analyzed retrospectively. The influencing factors leading to echocardiographic misdiagnosis were analyzed from the aspects of confusing image characteristics, special pathological anatomy of the left coronary artery (LCA), and operators' working years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Echocardiography diagnosed 11 cases with an accuracy rate of 68.8%. Five cases were misdiagnosed, three cases as endocardial fibroelastosis, one case as mitral prolapse with severe insufficiency, and one case as coronary\u2010pulmonary artery fistula. Display rate of the specific echocardiographic features for confirmed group and misdiagnosed group was statistically significantly different\uff08<jats:italic>P<\/jats:italic>\u00a0=\u00a0.014\uff09. But the working years of the operator for confirmed group and misdiagnosed group were not statistically significantly different\uff08<jats:italic>P<\/jats:italic>\u00a0=\u00a0.267\uff09. Some special pathological anatomy and pathophysiological features could be also the cause of misdiagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Echocardiography is the first diagnostic choice of the ALCAPA in China. It is essential for the operator to have the knowledge, diagnostic awareness, and proficiency in manipulation in the accurate interpretation of echocardiography results.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.14578","type":"journal-article","created":{"date-parts":[[2020,1,25]],"date-time":"2020-01-25T04:39:59Z","timestamp":1579927199000},"page":"104-113","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Misdiagnosis of anomalous origin of the left coronary artery from the pulmonary artery by echocardiography: Single\u2010center experience from China"],"prefix":"10.1111","volume":"37","author":[{"given":"Shan","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Ultrasound Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China"},{"name":"Hubei Province Key Laboratory of Molecular Imaging Wuhan 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