{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:26:52Z","timestamp":1756384012539,"version":"3.40.5"},"reference-count":20,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,8,20]],"date-time":"2020-08-20T00:00:00Z","timestamp":1597881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2020,9]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>There are limited data on the impact of right ventricular dysfunction (RVD) on the clinical outcomes in patients with stress cardiomyopathy (SC). The purpose of this study was to evaluate the impact of RVD on outcomes and to characterize the prognostic value of RV fractional area change (FAC).<\/jats:p><\/jats:sec>Methods<\/jats:title>This study retrospectively analyzed data from 111 consecutive patients with SC. The primary endpoint, major cardiac events (MCE), was a composite of 30\u2010day mortality, cardiogenic shock, life threatening arrhythmias, and stroke. Regression analysis was used to identify independent predictors of short (30\u00a0days)\u2010 and long\u2010term MCE.<\/jats:p><\/jats:sec>Results<\/jats:title>Among the 111 patients (80.2% females, mean age 45.8\u00a0\u00b1\u00a011.5\u00a0years), RVD was present in 17(15.3%) patients. MCE occurred in 18(16.2%) and 22(19.8%) patients at 30\u00a0days and during long\u2010term follow\u2010up, respectively. RVD was an independent predictor of short (HR 1.88(1.21\u201315.67), P<\/jats:italic>\u00a0=\u00a0.036)\u2010 and long (HR 1.65(1.11\u20139.67), P<\/jats:italic>\u00a0=\u00a0.016)\u2010term MCE. Compared with tricuspid annular plane systolic excursion\u00a0<\u00a015\u00a0mm (TAPSE) (sens 72.2%, spec 94.1%, AUC 0.75) and tricuspid annulus pulsed TDI\u2010derived peak systolic velocity (S\u2032)\u00a0<\u00a09.5\u00a0cm\/s (sens 67.2%, spec 94.5%, AUC 0.72), RV FAC\u00a0<\u00a030% (sens 89.1%, spec 100%, AUC 0.92) had the highest accuracy and discriminative ability to predict MCE. Furthermore, RV FAC\u00a0<\u00a030% was a significant predictor of recurrence (29.4% vs 2.1%, P<\/jats:italic>\u00a0=\u00a0.002) and delayed recovery time (21.4\u00a0\u00b1\u00a06.8 vs 8.5\u00a0\u00b1\u00a04.3\u00a0days, P<\/jats:italic>\u00a0<\u00a0.001).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>The presence of RVD in stress cardiomyopathy identifies patients at higher risk of mortality, complications, delayed recovery, and recurrence. Compared with other indices, RV FAC has the highest prognostic ability to predict these outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.14832","type":"journal-article","created":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T06:57:33Z","timestamp":1598597853000},"page":"1366-1373","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Right ventricular dysfunction in stress cardiomyopathy: The prognostic value of fractional area change"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7757-2785","authenticated-orcid":false,"given":"Muthiah","family":"Subramanian","sequence":"first","affiliation":[{"name":"Department of Cardiology at Amrita Institute of Medical Sciences Amritha Vishhwavidhyapeetham Kochi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisham","family":"Ahamed","sequence":"additional","affiliation":[{"name":"Department of Cardiology at Amrita Institute of Medical Sciences Amritha Vishhwavidhyapeetham Kochi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chirag","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Cardiology at Amrita Institute of Medical Sciences Amritha Vishhwavidhyapeetham Kochi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Navin","family":"Mathew","sequence":"additional","affiliation":[{"name":"Department of Cardiology at Amrita Institute of Medical Sciences Amritha Vishhwavidhyapeetham Kochi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajiv","family":"Chandrasekhar","sequence":"additional","affiliation":[{"name":"Department of Cardiology at Amrita Institute of Medical Sciences Amritha Vishhwavidhyapeetham Kochi 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