{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T10:59:33Z","timestamp":1788260373103,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T00:00:00Z","timestamp":1600905600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study sought to investigate the variation of right heart structure pre\u2010 and post\u2010operation as risk factors for moderate to severe pulmonary regurgitation (PR) after repaired Tetralogy of Fallot and the best \u201ccutoff\u201d values for the transannular patch (TAP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We collected surgical, echocardiographic, and computed tomographic data of Teralogy of Fallot (TOF) patients over two years and calculated z\u2010score values based on the echocardiographic data. Based on the PR level after follow\u2010up, the patients were divided into two groups, trivial to mild PR and moderate to severe PR. A multivariate logistic regression analysis was performed, and the receiver operating characteristic curve analysis was used to find the best \u201ccutoff\u201d value for risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 104 TOF patients were included in our cohort study. From the multivariate analysis, correction strategy (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.002), difference in zRVOT (OR 1.974, 95% CI 1.354 to 2.878, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.0001), and zPVA (OR 3.605, 95% CI 1.980 to 6.562, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.0001) were the significant risk factors for moderate to severe PR. The \"cutoff\" value for the difference in zPVA that could predict moderate to severe PR in the TAP group was 3, and the optimal \"cutoff\" value for TAP was \u22121.4.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The TAP is a risk factor for significant PR after surgery. We recommend the optimal \u201ccutoff\u201d value for TAP is \u22121.4 calculated using Shan\u2010Shan Wang\u2019s data set. During the procedure, to limit the RVOT resection and restrict the enlargement of pulmonary annulus within a variation of z\u2010score as 3 would reduce significant PR.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.14839","type":"journal-article","created":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T12:01:04Z","timestamp":1600948864000},"page":"1627-1633","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Pulmonary valve annular and right ventricular outflow tract size as predictions values for moderate to severe pulmonary regurgitation after repaired Tetralogy of Fallot"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0260-7901","authenticated-orcid":false,"given":"Mo\u2010Qi","family":"Li","sequence":"first","affiliation":[{"name":"Department of Pediatric Cardiology Beijing Anzhen Hospital Beijing Institute of Heart, Lung, and Blood Vessel Disease Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010Hong","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Beijing Anzhen Hospital Beijing Institute of Heart, Lung, and Blood Vessel Disease Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Beijing Anzhen Hospital Beijing Institute of Heart, Lung, and Blood Vessel Disease Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi\u2010Yuan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Beijing Anzhen Hospital Beijing Institute of Heart, Lung, and Blood Vessel Disease Capital Medical University  Beijing 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