{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T14:19:48Z","timestamp":1756995588957,"version":"3.40.5"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,4,20]],"date-time":"2021-04-20T00:00:00Z","timestamp":1618876800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Since mortality and morbidity of coronary artery disease are high, there is a need for non\u2010invasive diagnostic methods for early diagnosis and prediction of ischemic heart disease (IHD) outcome. This study aimed to assess the relationship between angiographic findings, the Presystolic wave (PSW) and some of the ischemic related parameters in echocardiography of the patients with chronic stable angina.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>This cross\u2010sectional study was conducted on the patients with chronic angina pectoris who referred to a tertiary hospital for coronary angiography in Mashhad, Iran. Demographic and medical history of the patients, as well as echocardiography findings, including ejection fraction (EF), regional wall motion abnormalities (RWMA), PSW and diastolic function were recorded. Angiographic findings, including SYNTAX score were also assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 220 patients (132 males and 88 females) with the mean age of 62.43\u00a0\u00b1\u00a011.40\u00a0years old participated in this study. The prevalence of PSW was 49.1%. The absence of the PSW was related to more RWMA (<jats:italic>P<\/jats:italic>\u00a0=.002), and higher stages of left ventricular diastolic dysfunction (LVDD) (<jats:italic>P<\/jats:italic>\u00a0=.029) and higher SYNTAX score (<jats:italic>P<\/jats:italic>\u00a0=.001). There was a significant association between the absence of the PSW and EF categories, especially in severe LV systolic dysfunction (LVEF\u00a0&lt;\u00a030%) (<jats:italic>P<\/jats:italic>\u00a0=.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The findings of this study revealed that PSW is strongly associated with the SYNTAX score. The absence of the PSW may indicate patients at high\u2010risk clinical status (higher SYNTAX score, severe systolic dysfunction, more RWMA, and higher stages of LVDD).<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.15045","type":"journal-article","created":{"date-parts":[[2021,4,21]],"date-time":"2021-04-21T07:29:38Z","timestamp":1618990178000},"page":"745-751","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Prevalence of the presystolic wave in echocardiography and its association with the extent of coronary artery disease in patients with chronic stable angina"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8826-2675","authenticated-orcid":false,"given":"Hedieh","family":"Alimi","sequence":"first","affiliation":[{"name":"Vascular and Endovascular Surgery Research Center Faculty of Medicine Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatemeh","family":"Hamidi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leila","family":"Bigdelue","sequence":"additional","affiliation":[{"name":"Vascular and Endovascular Surgery Research Center Faculty of Medicine Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hoorak","family":"Poorzand","sequence":"additional","affiliation":[{"name":"Vascular and Endovascular Surgery Research Center Faculty of Medicine Imam Reza Hospital Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fereshteh","family":"Ghaderi","sequence":"additional","affiliation":[{"name":"Vascular and Endovascular Surgery Research Center Faculty of Medicine Imam Reza Hospital Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afsoon","family":"Fazlinejad","sequence":"additional","affiliation":[{"name":"Vascular and Endovascular Surgery Research Center Faculty of Medicine Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohsen","family":"Muhebati","sequence":"additional","affiliation":[{"name":"Vascular and Endovascular Surgery Research Center Faculty of Medicine Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Emadzadeh","sequence":"additional","affiliation":[{"name":"Clinical Research Unit Faculty of Medicine Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,4,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.118.005375"},{"key":"e_1_2_7_3_1","first-page":"204","article-title":"Cardiovascular disease in iran in the last 40 years: prevalence, mortality, morbidity, challenges and strategies for cardiovascular prevention","volume":"22","author":"Sarrafzadegan N","year":"2019","journal-title":"Arch Iran Med"},{"key":"e_1_2_7_4_1","first-page":"91","article-title":"Gender related differences in clinical presentation of ischemic heart disease patients with concomitant chronic obstructive pulmonary disease","volume":"24","author":"Ashraf A","year":"2018","journal-title":"Pakistan J Chest Med"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/5723502"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.06.020"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.03.044"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.109.914051"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.02.018"},{"key":"e_1_2_7_10_1","first-page":"1","article-title":"The role of echocardiography in coronary artery disease and acute myocardial infarction","volume":"8","author":"Esmaeilzadeh M","year":"2013","journal-title":"J Tehran Univ Heart Center"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/16878507.2019.1594129"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.14217"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2014.08.048"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-017-1270-4"},{"key":"e_1_2_7_15_1","unstructured":"SYNTAX Score. Available at:http:\/\/www.syntaxscore.com.AccessedJanuary 17 2013"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2016.01.011"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2014.10.003"},{"key":"e_1_2_7_18_1","first-page":"113","article-title":"Presystolic wave is associated with subclinical left ventricular dysfunction assessed by myocardial performance index in type 2 diabetes mellitus","volume":"29","author":"Kul S","year":"2019","journal-title":"Arq Bras Cardiol"},{"key":"e_1_2_7_19_1","first-page":"167","article-title":"Left ventricular outflow tract velocity time integral in hospitalized heart failure with preserved ejection fraction","volume":"7","author":"Omote K","year":"2019","journal-title":"ESC Heart Failure"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.15045","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/echo.15045","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.15045","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T14:01:10Z","timestamp":1693576870000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.15045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,20]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1111\/echo.15045"],"URL":"https:\/\/doi.org\/10.1111\/echo.15045","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"type":"print","value":"0742-2822"},{"type":"electronic","value":"1540-8175"}],"subject":[],"published":{"date-parts":[[2021,4,20]]},"assertion":[{"value":"2020-11-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}