{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:24:06Z","timestamp":1787761446275,"version":"build-2784847793"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,5,8]],"date-time":"2021-05-08T00:00:00Z","timestamp":1620432000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["K23 HL146982"],"award-info":[{"award-number":["K23 HL146982"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["17MCPRP33630098"],"award-info":[{"award-number":["17MCPRP33630098"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR001073"],"award-info":[{"award-number":["UL1TR001073"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Data regarding the longitudinal relationship of global longitudinal strain (GLS) and echocardiographic parameters are lacking in peripartum cardiomyopathy (PPCM). We evaluated GLS and its correlation with change (\u2206) in left ventricular ejection fraction (LVEF).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively identified women age \u226516\u00a0years hospitalized at Montefiore Medical Center in Bronx, NY from 1999\u20102015 with International Statistical Classification of Diseases and Related Health Problems, 9th revision codes for PPCM or an occurrence of unexplained heart failure during or up to 5\u00a0months postpartum. N\u00a0=\u00a0195 charts were reviewed for inclusion\/exclusion criteria, n\u00a0=\u00a053 patients met criteria for PPCM, and of those, n\u00a0=\u00a013 had a baseline and follow\u2010up echocardiogram suitable for GLS analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of those eligible for strain analysis, the mean age was 30\u00a0\u00b1\u00a06\u00a0years, 46.2% identified as Black and 38.5% as Hispanic\/Latina. Baseline LVEF was 30 (25, 35)%, GLS was \u221213.2 (\u221214, \u22127.6)%. At a mean follow\u2010up time of 1.2\u00a0\u00b1\u00a00.7\u00a0years, 11\/13 had persistently mild \u221215.6 (\u221216.3, \u221212.7)%, and 2\/13 severely abnormal GLS \u22127.05 (\u22127.1, \u22127.0)%. There was no correlation between baseline GLS and \u2206LVEF (<jats:italic>r<\/jats:italic>\u00a0=\u00a0.014, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.965).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Global longitudinal strain is a sensitive method to identify subclinical myocardial dysfunction. In this series of women with PPCM, GLS remained persistently abnormal over time, even if LVEF improved. Future studies should examine the implication of persistently abnormal GLS in PPCM.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.15071","type":"journal-article","created":{"date-parts":[[2021,5,9]],"date-time":"2021-05-09T07:03:27Z","timestamp":1620543807000},"page":"885-891","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Persistence of abnormal global longitudinal strain in women with peripartum cardiomyopathy"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7983-5243","authenticated-orcid":false,"given":"Anna E.","family":"Bortnick","sequence":"first","affiliation":[{"name":"Division of Cardiology At Montefiore Medical Center and Albert Einstein College of Medicine Bronx NY USA"},{"name":"Division of Geriatrics At Montefiore Medical Center and Albert Einstein College of Medicine Bronx NY USA"},{"name":"Maternal Fetal Medicine\u2010Cardiology Joint Program At Montefiore Medical Center and Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Lama von Buchwald","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Cardiology Rush University Medical Center Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliaskar","family":"Hasani","sequence":"additional","affiliation":[{"name":"Department of Medicine At Montefiore Medical Center and Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Mount Sinai\/Morningside West New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia L.","family":"Berkowitz","sequence":"additional","affiliation":[{"name":"Department of Medicine Brown University Warren Alpert Medical School Providence 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