{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T17:03:36Z","timestamp":1756573416378},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,12,5]],"date-time":"2021-12-05T00:00:00Z","timestamp":1638662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Stroke is a leading cause of morbidity and mortality across the world and a significant portion of ischemic strokes have a cardiac source. We report a case of a 55\u2010year\u2010old male who presented with an ischemic stroke and bilateral pulmonary emboli secondary to an intra\u2010cardiac thrombus straddling a patent foramen ovale, which was clearly seen using transesophageal echocardiography. We discuss the management dilemma associated with this clinical picture given the risk of hemorrhagic transformation in the acute phase of an ischemic stroke. Our case demonstrates the need for a multidisciplinary approach in an area of medicine that lacks clear guidelines.<\/jats:p>","DOI":"10.1111\/echo.15269","type":"journal-article","created":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T04:15:04Z","timestamp":1638764104000},"page":"125-131","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Bi\u2010atrial thrombus straddling a patent foramen ovale with bilateral embolization: A therapeutic challenge"],"prefix":"10.1111","volume":"39","author":[{"given":"Abhishek","family":"Dattani","sequence":"first","affiliation":[{"name":"Department of Cardiology Glenfield Hospital  Leicester UK"},{"name":"Department of Cardiovascular Sciences University of Leicester  Leicester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kassem","family":"Safwan","sequence":"additional","affiliation":[{"name":"Department of Cardiology Glenfield Hospital  Leicester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammedimran","family":"Ansari","sequence":"additional","affiliation":[{"name":"Department of Cardiology Glenfield Hospital  Leicester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riyaz","family":"Somani","sequence":"additional","affiliation":[{"name":"Department of Cardiology Glenfield Hospital  Leicester UK"},{"name":"Department of Cardiovascular Sciences University of Leicester  Leicester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,5]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(19)30034-1"},{"key":"e_1_2_4_3_1","first-page":"1","article-title":"Stroke and transient ischaemic attack in over 16s: diagnosis and initial management","author":"NICE","year":"2019","journal-title":"NICE Guideline"},{"key":"e_1_2_4_4_1","volume-title":"Royal College of Physicians Intercollegiate Stroke Working Party","year":"2016"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11883-019-0790-x"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)04011-7"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000185730.50480.e7"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht134"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2013-204667"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2008.08.011"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.15269","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/echo.15269","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.15269","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T12:35:04Z","timestamp":1693226104000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.15269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,5]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1111\/echo.15269"],"URL":"https:\/\/doi.org\/10.1111\/echo.15269","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,5]]},"assertion":[{"value":"2021-09-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}