{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T08:09:40Z","timestamp":1788941380814,"version":"build-2803163510"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T00:00:00Z","timestamp":1642032000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cardiopulmonary ultrasound has shown varying results in the diagnosis of pulmonary embolism patients around the world. Hence, the current review was done to assess the diagnostic accuracy of cardiopulmonary ultrasound for diagnosis of pulmonary embolism among suspected patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a systematic search for all studies reporting the diagnostic accuracy of cardiopulmonary ultrasound for pulmonary embolism in the databases of MEDLINE, EMBASE, MEDLINE, SCOPUS, and Cochrane library from inception till May 2021. Meta\u2010analysis was performed using STATA software \u201cmidas\u201d package.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ten studies with 4216 patients were included. The pooled sensitivity was 77% (95% CI, 50\u201392%) and specificity was 99% (95% CI, 97\u2013100%), respectively. The pooled DOR was 382 (95% CI, 77\u20131883). Pooled LRP was 90 (95% CI, 24\u2013326) and pooled LRN was .23 (.09\u2013.58). There was significant heterogeneity found with the outcome with significant chi\u2010square test and I2 statistic\u00a0&gt;\u00a075%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cardiopulmonary ultrasound has the ability to be used as an adjunct to CTPA especially in resource constrained settings. Further reviews comparing multiple non\u2010invasive imaging modalities are required to pick the best tool for diagnosis of pulmonary embolism.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.15280","type":"journal-article","created":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T18:04:37Z","timestamp":1642097077000},"page":"185-193","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Diagnostic accuracy of cardiopulmonary ultrasound for pulmonary embolism: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"39","author":[{"given":"Jingli","family":"Cao","sequence":"first","affiliation":[{"name":"Department of Cardiac Intensive Care Unit RiZhao International Heart Hospital  RiZhao Shandong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junjie","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Shandong Province Yantai YuhuangDing Hospital  Yantai Shandong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Wang","sequence":"additional","affiliation":[{"name":"Cardiac Rehabilitation Center Rizhao International Heart Hospital  Rrizhao Shandong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7963-7052","authenticated-orcid":false,"given":"Lihong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Shandong Province Yantai YuhuangDing Hospital  Yantai Shandong China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,1,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1642036"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)07534-5"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/heart.85.2.229"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13089-015-0025-5"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13089-015-0025-5"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jth.12232"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.2147\/RMI.S40095"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-0447"},{"issue":"3","key":"e_1_2_7_10_1","first-page":"219","article-title":"Point\u2010of\u2010care ultrasound (POCUS): unnecessary gadgetry or evidence based medicine?","volume":"18","author":"Smallwood N","year":"2018","journal-title":"Clin Med J R Coll Physicians London"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2017.03.004"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-155-8-201110180-00009"},{"key":"e_1_2_7_13_1","first-page":"ED000142","article-title":"Updated guidance for trusted systematic reviews: a new edition of the cochrane handbook for systematic reviews of interventions","volume":"10","author":"Cumpston M","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0174581"},{"issue":"11","key":"e_1_2_7_15_1","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.5005\/jp-journals-10071-23661","article-title":"Impact of bedside combined cardiopulmonary ultrasound on etiological diagnosis and treatment of acute respiratory failure in critically ill patients","volume":"24","author":"Barman B","year":"2020","journal-title":"Indian J Crit Care Med"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14-0681"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2014.12.003"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.13-0797"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.13-0882"},{"key":"e_1_2_7_20_1","unstructured":"LaursenCB SlothE LassenAT et\u00a0al. Point\u2010of\u2010care ultrasonography in patients admitted with respiratory symptoms: a single\u2010blind randomised controlled trial.2014;2(August)."},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.13-1087"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13049-021-00872-8"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2017.02.003"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0235940"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2513-4"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1067\/j.cpradiol.2014.05.012"},{"key":"e_1_2_7_27_1","unstructured":"Recommended Curriculum Guidelines for Family Medicine Residents Point of Care Ultrasound. American Academy of Family Physicians. 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