{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T04:58:12Z","timestamp":1692939492891},"reference-count":11,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,6,25]],"date-time":"2022-06-25T00:00:00Z","timestamp":1656115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>COVID\u201019 related multisystem inflammatory syndrome in children (MIS\u2010C) can present with cardiovascular complications like shock, arrhythmias, pericardial effusion, and coronary artery dilatation. The majority of MIS\u2010C associated coronary artery abnormalities are dilation or small aneurysms which are transient and resolve in a few weeks. We present here a case of a 3\u2010month\u2010old child who was noted to have giant aneurysms of her coronary arteries (LAD and RCA) 26 days after testing positive for COVID\u201019. She was treated with IVIG, infliximab, and glucocorticoids along with aspirin, clopidogrel, and enoxaparin. She did not show any signs of coronary ischemia or cardiac dysfunction but continued to have persistent giant coronary artery aneurysms involving the LAD (z\u2010score \u223c35) and RCA (z\u2010score \u223c30). This study emphasizes the importance of early detection and aggressive management of MIS\u2010C to prevent potentially life\u2010threatening consequences.<\/jats:p>","DOI":"10.1111\/echo.15408","type":"journal-article","created":{"date-parts":[[2022,6,25]],"date-time":"2022-06-25T17:43:42Z","timestamp":1656179022000},"page":"950-953","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Giant coronary aneurysms in an infant: Dilemma of MIS\u2010C"],"prefix":"10.1111","volume":"39","author":[{"given":"Alexandra","family":"Drury","sequence":"first","affiliation":[{"name":"Washington State University\/Elson S. Floyd College of Medicine  Spokane Washington USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelsey","family":"Wold","sequence":"additional","affiliation":[{"name":"Kadlec Pediatric Cardiology  Richland Washington USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Healan","sequence":"additional","affiliation":[{"name":"Providence Medical Group\/Sacred Heart Medical Center  Spokane Washington USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashish","family":"Garg","sequence":"additional","affiliation":[{"name":"Washington State University\/Elson S. Floyd College of Medicine  Spokane Washington USA"},{"name":"Kadlec Pediatric Cardiology  Richland Washington USA"},{"name":"Providence Medical Group\/Sacred Heart Medical Center  Spokane Washington USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,6,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6932e2"},{"issue":"1","key":"e_1_2_7_3_1","first-page":"31","article-title":"Delayed Coronary Dilation with Multisystem Inflammatory Syndrome in Children","volume":"6","author":"Nelson MC","year":"2022","journal-title":"CASE (Phila)"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000002888"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.050065"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2021-050973"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40124-021-00258-5"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-021-03935-1"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-020-03766-6"},{"issue":"3","key":"e_1_2_7_10_1","first-page":"9","article-title":"A case of atypical Kawasaki disease with giant coronary artery aneurysm containing thrombus","volume":"18","author":"Micallef ES","year":"2016","journal-title":"Images Paediatr Cardiol"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.2091"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2021680"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.15408","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/echo.15408","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.15408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T14:03:31Z","timestamp":1692885811000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.15408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,25]]},"references-count":11,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["10.1111\/echo.15408"],"URL":"https:\/\/doi.org\/10.1111\/echo.15408","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,25]]},"assertion":[{"value":"2022-03-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}