{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:48:21Z","timestamp":1791910101278,"version":"4.3.4"},"reference-count":17,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,7,21]],"date-time":"2022-07-21T00:00:00Z","timestamp":1658361600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Trans\u2010catheter device closure of secundum type atrial septal defects (ASDs) has now become the treatment of choice. Device closure affects the hemodynamics and function of the heart. In the current study, we investigated the remodeling of the heart as assessed by advanced echocardiographic parameters following successful device closure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective cohort study was conducted and 45 patients who were eligible for ASD device closure were evaluated for volumetric, functional, Doppler, strain, and strain rate data of left and right atrium and ventricle pre\u2010procedural and 48 h post\u2010procedure<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In a prospective cohort study 45 patients who were eligible for ASD device closure; atrial and ventricular volumetric, functional, Doppler, strain, and strain rate data were recorded and compared pre\u2010procedurally and 48 h post\u2010procedure.We found significant changes in the left ventricular (LV) end diastolic volume index (<jats:italic>p<\/jats:italic>\u2010value = .03), right ventricular (RV) diameter (<jats:italic>p<\/jats:italic>\u2010value = &lt;.001), left atrial (LA) volume index (<jats:italic>p<\/jats:italic>\u2010value = .05), right atrial (RA) volume index (<jats:italic>p<\/jats:italic>\u2010value = .001), and right and left sided E\/e\u2019 ratio with a <jats:italic>p<\/jats:italic>\u2010value of .001 and .004, respectively. Our findings showed a significant reduction in the strains of the right and left atria and the right ventricular free wall after ASD device closure. LV global longitudinal strain decreased after the procedure but did not reach statistical significance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>ASD patients have impaired global strains compared to normal defined ranges. LA, RA, and RV strains show significant reduction after device closure. Decline in LA function following closure was greater in those with larger ASDs. In adult patients undergoing the procedure, abnormal LA function is a clinically relevant issue demanding pre and post\u2010 procedural precautions and treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.15421","type":"journal-article","created":{"date-parts":[[2022,7,21]],"date-time":"2022-07-21T11:45:42Z","timestamp":1658403942000},"page":"1089-1094","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Cardiac remodeling after atrial septal defects device closure"],"prefix":"10.1111","volume":"39","author":[{"given":"Tahereh","family":"Saedi","sequence":"first","affiliation":[{"name":"Echocardiography Fellowship, Rajaei Cardiovascular, Medical and Research Center Iran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ata","family":"Firouzi","sequence":"additional","affiliation":[{"name":"Cardiac Intervention Research Center, Rajaie Cardiovascular Medical &amp; Research Center Iran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sedigheh","family":"Saedi","sequence":"additional","affiliation":[{"name":"Rajaei Cardiovascular, Medical and Research Center Iran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,21]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"19","article-title":"Influence of percutaneous occlusion of atrial septal defect on left atrial function evaluated using 2D speckle tracking echocardiography","author":"Suzuki K","year":"2020","journal-title":"Int Heart J"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2018.08.111"},{"key":"e_1_2_7_4_1","first-page":"1","article-title":"Short\u2010and long\u2010term haemodynamic consequences of transcatheter closure of atrial septal defect and patent foramen ovale","author":"Jin X","year":"2021","journal-title":"Neth Heart J"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-017-1154-7"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jey042"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jum.14887"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/aca.ACA_153_17"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jeu089"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2016.09.007"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2011.01564.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-017-1217-9"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jex140"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.12693"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1464"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.01.029"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43044-020-00120-x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.repce.2017.06.010"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.15421","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/echo.15421","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.15421","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T17:40:59Z","timestamp":1692726059000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.15421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,21]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1111\/echo.15421"],"URL":"https:\/\/doi.org\/10.1111\/echo.15421","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,21]]},"assertion":[{"value":"2022-03-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}