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MR produces chronic and progressive volume overload with left atrial (LA) and left ventricular (LV) dilatation and dysfunction, atrial fibrillation (AF) and eventually myocardial fibrosis, irrespective of ejection fraction (EF). Surgical correction (mitral valve repair) of MR removes the volume overload, hence unmasks pre\u2010operative LV structure and function disturbances, including reduced EF and global longitudinal and circumferential strain, as well as LA volume and strain. This review aims at describing LA remodeling before and after surgical repair.<\/jats:p>","DOI":"10.1111\/echo.15452","type":"journal-article","created":{"date-parts":[[2022,9,8]],"date-time":"2022-09-08T13:48:02Z","timestamp":1662644882000},"page":"1264-1268","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Left atrial myocardial intrinsic function remodeling response to repair of primary mitral regurgitation"],"prefix":"10.1111","volume":"39","author":[{"given":"Matteo","family":"Lisi","sequence":"first","affiliation":[{"name":"Department of Medical Biotechnologies Division of Cardiology University of Siena  Siena Italy"},{"name":"Department of Cardiovascular Disease \u2013 AUSL Romagna Division of Cardiology Ospedale S. 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