{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T14:22:31Z","timestamp":1790432551525,"version":"4.1.0"},"reference-count":38,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,10,6]],"date-time":"2022-10-06T00:00:00Z","timestamp":1665014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Left ventricular diastolic dysfunction (LVDD) is associated with poor outcomes in the intensive care unit (ICU). Nonetheless, precise reporting of LVDD in COVID\u201019 patients is currently lacking and assessment could be challenging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed an echocardiography study in COVID\u201019 patients admitted to ICU with the aim to describe the feasibility of full or simplified LVDD assessment and its incidence. We also evaluated the association of LVDD or of single echocardiographic parameters with hospital mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Between 06.10.2020 and 18.02.2021, full diastolic assessment was feasible in 74% (<jats:italic>n<\/jats:italic>\u00a0=\u00a026\/35) of patients receiving a full echocardiogram study. LVDD incidence was 46% (<jats:italic>n<\/jats:italic>\u00a0=\u00a012\/26), while the simplified assessment produced different results (incidence 81%, <jats:italic>n<\/jats:italic>\u00a0=\u00a021\/26). Nine patients with normal function on full assessment had LVDD with simplified criteria (grade I\u00a0=\u00a02; grade II\u00a0=\u00a03; grade III\u00a0=\u00a04). Nine patients were hospital\u2010survivors (39%); the incidence of LVDD (full assessment) was not different between survivors (<jats:italic>n<\/jats:italic>\u00a0=\u00a02\/9, 22%) and non\u2010survivors (<jats:italic>n<\/jats:italic>\u00a0=\u00a010\/17, 59%; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.11). The E\/e\u2019 ratio lateral was lower in survivors (7.4 [3.6] vs. non\u2010survivors 10.5 [6.3], <jats:italic>p<\/jats:italic>\u00a0=\u00a0.03). We also found that s\u2019 wave was higher in survivors (average, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In a small single\u2010center study, assessment of LVDD according to the latest guidelines was feasible in three quarters of COVID\u201019 patients. Non\u2010survivors showed a trend toward greater LVDD incidence; moreover, they had significantly worse s\u2019 values (all) and higher E\/e\u2019 ratio (lateral).<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.15462","type":"journal-article","created":{"date-parts":[[2022,10,6]],"date-time":"2022-10-06T09:28:23Z","timestamp":1665048503000},"page":"1391-1400","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Full and simplified assessment of left ventricular diastolic function in covid\u201019 patients admitted to ICU: Feasibility, incidence, and association with mortality"],"prefix":"10.1111","volume":"39","author":[{"given":"Luigi","family":"La Via","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Intensive Care \u201cPoliclinico\u2010San Marco\u201d University Hospital  Catania Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica","family":"Dezio","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care \u201cPoliclinico\u2010San Marco\u201d University Hospital  Catania Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Santonocito","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care \u201cPoliclinico\u2010San Marco\u201d University Hospital  Catania Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marinella","family":"Astuto","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care \u201cPoliclinico\u2010San Marco\u201d University Hospital  Catania Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Morelli","sequence":"additional","affiliation":[{"name":"Department Clinical Internal, Anesthesiological and Cardiovascular Sciences, University of Rome \u201cLa Sapienza\u201d, Policlinico Umberto Primo  Roma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Huang","sequence":"additional","affiliation":[{"name":"Intensive Care Medicine, Nepean Hospital The University of Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Vieillard\u2010Baron","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Intensive R\u00e9animation, Assistance Publique\u2010H\u00f4pitaux de Paris University Hospital Ambroise Par\u00e9  Boulogne\u2010Billancourt France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Sanfilippo","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care \u201cPoliclinico\u2010San Marco\u201d University Hospital  Catania Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,6]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"Center for Systems Science and Engineering at Johns Hopkins University.COVID\u201019 Map. 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