{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T16:58:41Z","timestamp":1778173121165,"version":"3.51.4"},"reference-count":28,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,10,20]],"date-time":"2022-10-20T00:00:00Z","timestamp":1666224000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Cardiac involvement in recovered COVID\u201019 patients assessed by cardiac magnetic resonance imaging (MRI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Subjects recently recovered from COVID\u201019 and with an abnormal left ventricular global longitudinal strain were enrolled. Cardiac MRI in all the enrolled subjects was done at baseline (within 30\u201390 days following recovery from COVID\u201019) with a follow\u2010up scan at 6 months in individuals with an abnormal baseline scan. Additionally, 20 age\u2010and sex\u2010matched individuals were enrolled as healthy controls (HCs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All the 30 enrolled subjects were symptomatic during active COVID\u201019 disease and were categorized as mild: 11 (36.7%), moderate: 6 (20%), and severe: 13 (43.3%). Of the 30 patients, 16 (53.3%) had abnormal CMR findings. Myocardial edema was reported in 12 (40%) patients while 10 (33.3%) had late gadolinium enhancement (LGE). No difference was observed in terms of conventional left ventricular (LV) parameters; however, COVID\u201019\u2010recovered patients had significantly lower right ventricular (RV) ejection fraction, RV stroke volume, and RV cardiac index compared to HCs. Follow\u2010up scan was abnormal in 4\/16 (25%) with LGE persisting in three patients (who had severe COVID\u201019 [3\/4;75%]). Subjects with severe COVID\u201019 had a greater frequency of LGE (53.8%) and myocardial edema (61.5%) as compared to mild and moderate cases. Myocardial T1 (1284\u00a0\u00b1\u00a043.8\u00a0ms vs. 1147.6\u00a0\u00b1\u00a068.4\u00a0ms; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.0001) and T2 values (50.8\u00a0\u00b1\u00a016.7\u00a0ms vs. 42.6\u00a0\u00b1\u00a03.6\u00a0ms; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.04) were significantly higher in post COVID\u201019 subjects compared to HCs. Similarly, T1 and T2 values of severe COVID\u201019 patients were significantly higher compared to mild and moderate cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>An abnormal CMR was seen in half of the recovered patients with persistent abnormality in one\u2010fourth at 6 months. Our study suggests a need for closer follow\u2010up among recovered subjects in order to evaluate for long\u2010term cardiovascular sequelae. COVID\u201019 causes structural changes in the myocardium in a small segment of patients with partial spontaneous resolution.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.15466","type":"journal-article","created":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T03:44:22Z","timestamp":1666323862000},"page":"1401-1411","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Role of cardiovascular magnetic resonance imaging in COVID\u201019 recovered patients: A short\u2010term follow\u2010up study"],"prefix":"10.1111","volume":"39","author":[{"given":"Shekhar","family":"Kunal","sequence":"first","affiliation":[{"name":"Department of Cardiology Govind Ballabh\u00a0Pant Institute of Post Graduate Medical Education and Research  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prachi","family":"Bagarhatta","sequence":"additional","affiliation":[{"name":"Department of Medicine Maulana Azad Medical College  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Girish M.","family":"Palleda","sequence":"additional","affiliation":[{"name":"Department of Cardiology Govind Ballabh\u00a0Pant Institute of Post Graduate Medical Education and Research  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ankit","family":"Bansal","sequence":"additional","affiliation":[{"name":"Department of Cardiology Govind Ballabh\u00a0Pant Institute of Post Graduate Medical Education and Research  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishal","family":"Batra","sequence":"additional","affiliation":[{"name":"Department of Cardiology Govind Ballabh\u00a0Pant Institute of Post Graduate Medical Education and Research  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mradul K.","family":"Daga","sequence":"additional","affiliation":[{"name":"Department of Medicine Maulana Azad Medical College  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay","family":"Tyagi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Govind Ballabh\u00a0Pant Institute of Post Graduate Medical Education and Research  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashok","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis Govind Ballabh\u00a0Pant Institute of Post Graduate Medical Education and Research  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kalpana","family":"Bansal","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis Govind Ballabh\u00a0Pant Institute of Post Graduate Medical Education and Research  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ritu","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis Eternal Heart Care Center (EHCC)  Jaipur Rajasthan India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohit D.","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Cardiology Govind Ballabh\u00a0Pant Institute of Post Graduate Medical Education and Research  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,10,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2012-7"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-020-0413-9"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/postgradmedj-2020-139585"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.15199"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2020.0950"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ihj.2020.10.005"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41747-021-00208-2"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2020.3557"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2020.05.004"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2020.7444"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.27534"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-021-00710-x"},{"key":"e_1_2_7_14_1","first-page":"539","article-title":"American heart association writing group on myocardial segmentation and registration for cardiac imaging. standardized myocardial segmentation and nomenclature for tomographic imaging of the heart. 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