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While left ventricular ejection fraction (LVEF) derived from TTE is a very well\u2010understood parameter, limitations such as high inter and intra\u2010observer variability, insensitivity to sub\u2010clinical dysfunction, and influence of loading conditions make LVEF a complicated and unreliable parameter. Myocardial deformation imaging has been identified as a promising parameter for identifying subclinical left ventricular dysfunction, however, this parameter is still afterload dependent. Myocardial Work is a promising novel assessment technique that accounts for afterload by combining the use of myocardial deformation imaging and non\u2010invasive blood pressure to provide a more comprehensive assessment of mechanics beyond LVEF. This review evaluates the evidence for various echocardiographic assessment parameters used to quantify left ventricular function including myocardial work in patients with AS.<\/jats:p>","DOI":"10.1111\/echo.15497","type":"journal-article","created":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T06:35:39Z","timestamp":1669790139000},"page":"1470-1480","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Current and novel echocardiographic assessment of left ventricular systolic function in aortic stenosis\u2014A comprehensive review"],"prefix":"10.1111","volume":"39","author":[{"given":"Peter","family":"Luke","sequence":"first","affiliation":[{"name":"School of Biomedical Science Nutritional and Sport Sciences Newcastle University  Newcastle upon Tyne UK"},{"name":"Newcastle upon Tyne Hospital Trust Freeman Hospital  Newcastle upon Tyne 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