{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T17:41:23Z","timestamp":1763142083780,"version":"3.40.5"},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,6,6]],"date-time":"2023-06-06T00:00:00Z","timestamp":1686009600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Prolonged endurance exercise increase the risk of atrial fibrillation (AF) in men. Functional parameters may help separate physiological from pathological atrial remodeling in athletes. LA mechanical dispersion (LA MD) is associated with AF in the general population, but the associations between prolonged exercise, LA MD and AF are not known.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To describe LA MD in veteran athletes with and without paroxysmal AF (pAF) and to investigate LA MD's ability to identify veteran athletes with pAF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two hundred and ninety\u2010three men, skiers with (<jats:italic>n<\/jats:italic>\u00a0=\u00a057) and without (<jats:italic>n<\/jats:italic>\u00a0=\u00a087) pAF, and controls with (<jats:italic>n<\/jats:italic>\u00a0=\u00a061) and without pAF (<jats:italic>n<\/jats:italic>\u00a0=\u00a088) underwent an echocardiographic exam in sinus rhythm. LA reservoir strain (LASr) was measured, and LA MD defined as the standard deviation of time\u2010to\u2010peak strain (SD\u2010TPS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Skiers (mean age 70.7\u00a0\u00b1\u00a06.7 years) reported an average of 40\u201350 years of endurance exercise. LA volumes were associated with pAF and athletic status (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001). SD\u2010TPS was associated with pAF (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001) but not athletic status (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.173). We found no significant trend between years of exercise and SD\u2010TPS in individuals without AF (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.893). SD\u2010TPS did not add incremental value in identifying athletes with pAF in addition to clinical markers, QRS width, LA volume, and LASr (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.056).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LA MD was associated with pAF regardless of athletic status but not related to years of endurance exercise, suggesting LA MD could be a promising marker of pathological atrial remodeling in athletes. However, we found no incremental value of LA MD identifying athletes with pAF when LASr was included in the model.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.15634","type":"journal-article","created":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T12:54:47Z","timestamp":1686142487000},"page":"679-686","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Left atrial dyssynchrony in veteran endurance athletes with and without paroxysmal atrial fibrillation"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4801-6146","authenticated-orcid":false,"given":"Eivind","family":"S\u00f8rensen","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Diakonhjemmet Hospital  Oslo Norway"},{"name":"Department of Medical Research B\u00e6rum Hospital Vestre Viken Hospital Trust  Gjettum Norway"},{"name":"Institute of Clinical Medicine University of Oslo  Oslo 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