{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T03:34:57Z","timestamp":1791603297313,"version":"4.3.4"},"reference-count":31,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T00:00:00Z","timestamp":1691366400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Overweightness is a considerable step in the process leading to obesity. There are no sufficient studies on the effect of cardiomyopathy defined in obese patients about overweight subjects. We thought that it may be useful to examine the myocardial involvement in overweight individuals electro\u2010mechanically with more sensitive techniques before the development of obesity cardiomyopathy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of the present study was to demonstrate whether or not there are subclinical left ventricular (LV) electrical and mechanical dysfunctions in overweight patients using frontal QRS\u2010T (fQRS\u2010T) angle (electrically) and 3D\u2010speckle tracking echocardiography (mechanically).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 80 overweight patients and 80 age\u2010 and sex\u2010matched normal weight individuals were enrolled into the study. 3D\u2010STE examinations of the patients were performed. Electrocardiographic recordings were obtained for fQRS\u2010T angle assessment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The LV\u2010GLS and LV\u2010GCS were significantly depressed in the overweight group than in the normal weight group (\u221214.5\u00a0\u00b1\u00a03.4\u00a0vs. \u221221.7\u00a0\u00b1\u00a03.6, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001; \u221215.2\u00a0\u00b1\u00a04.6\u00a0vs. \u221224.3\u00a0\u00b1\u00a04.8, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001, respectively). The fQRS\u2010T angle was found to be increased in the overweight group (142.5\u00a0\u00b1\u00a039.2\u00a0vs. 114.7\u00a0\u00b1\u00a043.5, <jats:italic>p<\/jats:italic>\u00a0=\u00a0&lt;\u00a0.001). Statistically significant positive linear correlations were observed between BMI with LV\u2010GLS, LV\u2010GCS, and fQRS\u2010T angle. LV\u2010GLS and LV\u2010GCS were found to be disrupted linearly as BMI increased (<jats:italic>r<\/jats:italic>\u00a0=\u00a0.718 for BMI and LV\u2010GLS, <jats:italic>r<\/jats:italic>\u00a0=\u00a0.653 for BMI and LV\u2010GCS). As BMI increased, it was found that the fQRS\u2010T angle increased (<jats:italic>r<\/jats:italic>\u00a0=\u00a0.692 for BMI and fQRS\u2010T angle).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our results support that, overweight individuals, despite their being apparently healthy, may have subclinical LV myocardial mechanical and electrical dysfunction.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.15667","type":"journal-article","created":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T08:29:39Z","timestamp":1691396979000},"page":"969-975","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Demonstration of subclinical left ventricular electrical and mechanical dysfunction in overweight subjects by frontal QRS\u2010T angle and 3D\u2010speckle tracking echocardiography"],"prefix":"10.1111","volume":"40","author":[{"given":"Ganbar","family":"Mammadov","sequence":"first","affiliation":[{"name":"Faculty of Medicine Department of Cardiology Izmir University of Economics Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ugur","family":"Taskin","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Department of Cardiology Izmir University of Economics Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferhat","family":"Dindas","sequence":"additional","affiliation":[{"name":"Department of Cardiology Training and Research Hospital Usak University Usak Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3895-1923","authenticated-orcid":false,"given":"Mustafa","family":"Dogdus","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Department of Cardiology Izmir University of Economics Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,8,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.12.068"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00017.2007"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.733451"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/0366-6999.187844"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(85)90244-9"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000453267"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2011.157"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2011.05.042"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.12485"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/anec.12206"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0136174"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2013.08.017"},{"key":"e_1_2_10_14_1","first-page":"353","article-title":"An analysis of the time relations of electrocardiograms","volume":"7","author":"Bazett HC","year":"1920","journal-title":"Heart"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2011.11.010"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00017.2007"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.05.060"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcm.2008.10.001"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.07.037"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.13764"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2012.01773.x"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jet103"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-020-02008-y"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.14214"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-019-01760-0"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-014-0429-5"},{"issue":"4","key":"e_1_2_10_27_1","first-page":"180","article-title":"Evaluation of subclinical left ventricular dysfunction in overweight people with 3D speckle\u2010tracking echocardiography","volume":"21","author":"Dogdus M","year":"2019","journal-title":"Anatol J Cardiol"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.11.1252"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.03.104"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00096.2015"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2011.07.030"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2018.08.060"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.15667","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T14:42:05Z","timestamp":1694097725000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.15667"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,7]]},"references-count":31,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1111\/echo.15667"],"URL":"https:\/\/doi.org\/10.1111\/echo.15667","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,7]]},"assertion":[{"value":"2023-04-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}