{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:52:53Z","timestamp":1787165573362,"version":"build-2736575974"},"reference-count":47,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,1,24]],"date-time":"2024-01-24T00:00:00Z","timestamp":1706054400000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>No study has focused on left atrial (LA) function assessed by echocardiography in adult patients with simple D\u2010TGA after arterial switch operation (ASO). We aimed to describe LA strain parameters in these patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective cohort study including 42 adult patients with simple D\u2010TGA after ASO and 33 aged\u2010matched controls. Phasic LA and LV global longitudinal strain (GLS) were obtained by transthoracic 2D\u2010speckle tracking echocardiography (STE). Volumetric and functional analysis of LA and LV were also evaluated by 2D and 3D analysis. A multivariable model was performed to investigate the variables that best differentiate patients with D\u2010TGA from healthy controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      LA strain parameters in D\u2010TGA patients were within the normal range described for healthy subjects. However, the three LA strain parameters (Reservoir, Conduit, and Contraction) were lower in patients (LASr: 31.13\u00a0\u00b1\u00a07.67\u00a0vs. 49.71\u00a0\u00b1\u00a08.38; LAS cd: \u201022.91\u00a0\u00b1\u00a05.69\u00a0vs. \u201034.55\u00a0\u00b1\u00a06.54; LASct: \u20108.14\u00a0\u00b1\u00a04.93\u00a0vs. \u201015.15\u00a0\u00b1\u00a06.07,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.001 for all three comparisons). LA volumes were similar between patients and controls.\n                    <\/jats:p>\n                    <jats:p>\n                      LV\u2010GLS remained significantly lower in the D\u2010TGA group than in controls (\u201017.29\u00a0\u00b1\u00a02.68\u00a0vs. \u201021.98\u00a0\u00b1\u00a01.84,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.001).\n                    <\/jats:p>\n                    <jats:p>\n                      D\u2010TGA patients had evidence of worse LV ejection fraction measured by the Teichholz method (63.38\u00a0\u00b1\u00a08.23\u00a0vs. 69.28\u00a0\u00b1\u00a05.92,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.001) and 3D analysis (57.97%\u00a0\u00b1\u00a04.16\u00a0vs. 60.67\u00a0\u00b1\u00a03.39,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.011) and diastolic dysfunction as compared to healthy controls.\n                    <\/jats:p>\n                    <jats:p>LV\u2010GLS and conduit LAS were the variables best differentiating patients with D\u2010TGA from healthy controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>LA strain is impaired in young adults with simple D\u2010TGA late after the ASO, probably in agreement with some degree of LV dysfunction previously described.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/echo.15750","type":"journal-article","created":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T00:49:47Z","timestamp":1706143787000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Left atrial strain in adults after the arterial switch operation for transposition of the great arteries"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0616-2986","authenticated-orcid":false,"given":"Francisco","family":"Buend\u00eda\u2010Fuentes","sequence":"first","affiliation":[{"name":"Cardiology Department Hospital Universitari i Politecnic La Fe  Valencia Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red en Enfermedades Cardiovasculares (CIBERCV)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Lozano\u2010Edo","sequence":"additional","affiliation":[{"name":"Cardiology Department Hospital Universitari i Politecnic La Fe  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Jover\u2010Pastor","sequence":"additional","affiliation":[{"name":"Cardiology Department Hospital Universitari i Politecnic La Fe  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 C.","family":"S\u00e1nchez\u2010Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Cardiology Department Hospital Universitari i Politecnic La Fe  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Mart\u00ednez\u2010Sole","sequence":"additional","affiliation":[{"name":"Cardiology Department Hospital Universitari i Politecnic La Fe  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Rodr\u00edguez\u2010Serrano","sequence":"additional","affiliation":[{"name":"Cardiology Department Hospital Universitari i Politecnic La Fe  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaume","family":"Aguero","sequence":"additional","affiliation":[{"name":"Cardiology Department Hospital Universitari i Politecnic La Fe  Valencia Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red en Enfermedades Cardiovasculares (CIBERCV)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel A.","family":"Arnau\u2010Vives","sequence":"additional","affiliation":[{"name":"Cardiology Department Hospital Universitari i Politecnic La Fe  Valencia Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red en Enfermedades Cardiovasculares (CIBERCV)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Osa\u2010S\u00e1ez","sequence":"additional","affiliation":[{"name":"Cardiology Department Hospital Universitari i Politecnic La Fe  Valencia Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red en Enfermedades Cardiovasculares (CIBERCV)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis V.","family":"Mart\u00ednez\u2010Dolz","sequence":"additional","affiliation":[{"name":"Cardiology Department Hospital Universitari i Politecnic La Fe  Valencia Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red 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