{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T22:53:53Z","timestamp":1785365633150,"version":"3.55.0"},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,2,8]],"date-time":"2024-02-08T00:00:00Z","timestamp":1707350400000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There are various ways that coronary artery disease (CAD) might present itself. Individual risk stratification for non ST\u2010elevation\u2010acute coronary syndrome (NSTE\u2010ACS) patients should determine whether invasive coronary angiography and revascularization should be scheduled.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim of work<\/jats:title><jats:p>To assess the possible utility of left ventricular global longitudinal strain in the risk\u2010stratifying process of NSTE\u2010ACS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and methods<\/jats:title><jats:p>The cardiology department of Zagazig University in Egypt organized and oversaw this cross\u2010sectional study. The practical portion was carried out on 90 patients with NSTE\u2010ACS based on European society of cardiology (ESC) guidelines (and they agreed for invasive strategy) between May 2019 and December 2020 at Salalah Heart Center in Sultanate of Oman. All patients underwent a full clinical examination, 12\u2010lead ECG, and serial high\u2010sensitivity troponin T (hs\u2010TnT) in addition to a thorough history taking process. On patient's admission, the GRACE risk score was assessed. All patients who were suspected of having NSTE\u2010ACS upon admission underwent transthoracic echocardiography, including two\u2010dimensional speckle tracking (2D\u2010ST). Left ventricular global longitudinal strain (LV\u2010GLS %) was measured and analyzed using 2D speckle tracking. SYNTAX Score was determined for all patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>By analysis of the performance of LV\u2010GLS% in prediction of high risk by GRACE score, we found that with cutoff (\u2265\u201013.8), the AUC was (0.944) with sensitivity, specificity, PPV, NPV, and accuracy (0.944, 93.3%, 84%, 53.8%, 98.4%, 85.6%), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Global longitudinal strain can predict accurately high\u2010risk NSTE\u2010ACS patients by GRACE score.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.15769","type":"journal-article","created":{"date-parts":[[2024,2,8]],"date-time":"2024-02-08T17:37:36Z","timestamp":1707413856000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The possible utility of global longitudinal strain in the risk\u2010stratifying process of non\u2010ST elevation\u2010acute coronary syndrome"],"prefix":"10.1111","volume":"41","author":[{"given":"Ahmed","family":"Fouad","sequence":"first","affiliation":[{"name":"Salalah Heart Center  Salalah Oman"},{"name":"Sednawy Health Insurance Hospital  Zagazig Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsayed Mohamad","family":"Farag","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Zagazig University  Zagazig Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisham Samir","family":"Roshdy","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Zagazig University  Zagazig Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwa Mohamad","family":"Gad","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Zagazig University  Zagazig Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Said","family":"Almaashani","sequence":"additional","affiliation":[{"name":"Salalah Heart Center  Salalah Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amro","family":"Sayed","sequence":"additional","affiliation":[{"name":"Salalah Heart Center  Salalah Oman"},{"name":"Faculty of Medicine Assiut University  Assiut Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1714\/2464.25804"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.114.000981"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.2001.2738"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.4070\/kcj.2016.46.5.639"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2013.01.009"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa909"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2016.08.001"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43044\u2010020\u201000064\u20102"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1530\/ERP\u201016\u20100005"},{"key":"e_1_2_10_11_1","volume-title":"Non ST segment elevation myocardial infarction. 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