{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:03:29Z","timestamp":1791813809316,"version":"4.3.4"},"reference-count":39,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T00:00:00Z","timestamp":1720483200000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Evaluation of the fetal heart involves two approaches. The first describes a screening protocol in which the heart is imaged in transverse planes that includes the four\u2010chamber view (4CV), left and right outflow tracts, and the 3\u2010vessel\u2010tracheal view. The second approach is a fetal echocardiogram that requires additional cardiac images as well as evaluating ventricular function using diagnostic tools such as M\u2010mode and pulsed Doppler ultrasound. Speckle tracking analysis of the ventricular and atrial endocardium of the fetal heart has focused primarily on computing longitudinal global strain. However, the technology enabling this measurement to occur has recently been adapted to enable the clinician to obtain numerous additional measurements of the size, shape, and contractility of the ventricles and atrial chambers. By using the increased number of measurements derived from speckle tracking analysis, we have reported the ability to screen for tetralogy of Fallot, D\u2010transposition of the great arteries (D\u2010TGA), and coarctation of the aorta by only imaging the 4CV. In addition, we have found that measurements derived from speckle tracking analysis of the ventricular and atrial chambers can be used to compute the risk for emergent neonatal balloon atrial septostomy in fetuses with D\u2010TGA. The purpose of this review is to consolidate our experience in one source to provide perspective on the benefits of speckle tracking analysis to measure the size, shape, and contractility of the ventricles and atria imaged in the 4CV in fetuses with congenital heart defects.<\/jats:p>","DOI":"10.1111\/echo.15870","type":"journal-article","created":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T11:11:51Z","timestamp":1720523511000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Review of speckle tracking analysis to measure the size, shape, and contractility of the fetal heart in fetuses with congenital heart defects"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8814-572X","authenticated-orcid":false,"given":"Greggory R.","family":"DeVore","sequence":"first","affiliation":[{"name":"Fetal Diagnostic Centers  Pasadena California USA"},{"name":"Department of Obstetrics and Gynecology Wayne State University  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berthold","family":"Klas","sequence":"additional","affiliation":[{"name":"TomTec Corporation  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina","family":"Cuneo","sequence":"additional","affiliation":[{"name":"Department of Surgery College of Medicine, University of Arizona  Tucson Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Satou","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Department of Pediatrics UCLA Mattel Children's Hospital David Geffen School of Medicine at UCLA  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Sklansky","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Department of Pediatrics UCLA Mattel Children's Hospital David Geffen School of Medicine at UCLA  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,9]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/Uog.26224"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/Jum.15163"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.Cir.0000437597.44550.5d"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/Jum.15188"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.Echo.2023.04.014"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.7863\/Ultra.15.08060"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/Jum.15561"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/Uog.17505"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/Pd.5166"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/Echo.15533"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.7863\/Ultra.16.02019"},{"key":"e_1_2_3_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/Pd.4980"},{"key":"e_1_2_3_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/Jum.14261"},{"key":"e_1_2_3_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/Jum.14792"},{"key":"e_1_2_3_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/Jum.14799"},{"key":"e_1_2_3_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/Jum.15888"},{"key":"e_1_2_3_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/Jum.14454"},{"key":"e_1_2_3_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/Jum.14455"},{"key":"e_1_2_3_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/Jum.14811"},{"key":"e_1_2_3_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/Uog.19048"},{"key":"e_1_2_3_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/Jum.15639"},{"key":"e_1_2_3_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/Jum.16060"},{"key":"e_1_2_3_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/S00246\u2010023\u201003131\u2010Y"},{"key":"e_1_2_3_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/Uog.21989"},{"key":"e_1_2_3_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.Echo.2012.06.005"},{"key":"e_1_2_3_27_1","doi-asserted-by":"publisher","DOI":"10.1159\/000334413"},{"key":"e_1_2_3_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.Echo.2013.06.007"},{"key":"e_1_2_3_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.Echo.2012.10.007"},{"key":"e_1_2_3_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.Echo.2014.06.012"},{"key":"e_1_2_3_31_1","doi-asserted-by":"publisher","DOI":"10.1161\/Circimaging.114.002110"},{"key":"e_1_2_3_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/Uog.15971"},{"key":"e_1_2_3_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/Uog.15939"},{"key":"e_1_2_3_34_1","doi-asserted-by":"publisher","DOI":"10.1371\/Journal.Pone.0199581"},{"key":"e_1_2_3_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/Uog.19183"},{"key":"e_1_2_3_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.Ultrasmedbio.2018.09.013"},{"key":"e_1_2_3_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.Earlhumdev.2020.105160"},{"key":"e_1_2_3_38_1","doi-asserted-by":"publisher","DOI":"10.3389\/Fcvm.2021.764676"},{"key":"e_1_2_3_39_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2023.2214663"},{"key":"e_1_2_3_40_1","doi-asserted-by":"publisher","DOI":"10.1515\/Jpm\u20102022\u20100379"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.15870","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T14:44:34Z","timestamp":1721054674000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.15870"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":39,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1111\/echo.15870"],"URL":"https:\/\/doi.org\/10.1111\/echo.15870","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"2024-05-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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