{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T22:38:08Z","timestamp":1783377488170,"version":"3.54.6"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T00:00:00Z","timestamp":1740096000000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Routine radiofrequency catheter ablation relies on x\u2010ray imaging, which may increase the risk of radiation exposure to patients. With the rapid development of intracardiac echocardiography (ICE) technology, it provides a new guidance modality for radiofrequency catheter ablation and shows great potential for application in the treatment of atrial fibrillation (AF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the efficacy and safety of intracardiac echocardiography guided radiofrequency catheter ablation for the treatment of AF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective cohort study was used to collect 184 patients who underwent radiofrequency catheter ablation for the treatment of AF from January 2020 to September 2021 in the cardiovascular medicine department of our hospital. According to whether they used ICE or not, they were divided into the ICE group (30 cases) and the non\u2010ICE group (154 cases). The procedure of the intervention, complications during the intervention and follow\u2010up periods, use of early anticoagulation and antiarrhythmic medications, and the success rate of AF ablation 1 year after the intervention were compared between the two groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In comparison to the non\u2010ICE group, the septal puncture time (6.27 \u00b1 1.91\u00a0min vs. 7.21 \u00b1 2.08\u00a0min,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.022), left atrial modeling time (4.93 \u00b1 1.84\u00a0min vs. 5.75 \u00b1 1.96\u00a0min,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.035), and total ablation time (67.73 \u00b1 2.64\u00a0min vs. 73.35 \u00b1 1.96\u00a0min,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001) in the ICE group were significantly reduced. Radiation exposure time (5.09 \u00b1 0.23\u00a0min vs. 13.17 \u00b1 0.28\u00a0min,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001) and radiation exposure (33.13 \u00b1 1.99 mGy\/cm\n                      <jats:sup>2<\/jats:sup>\n                      vs. 217.6 \u00b1 15.17 mGy\/cm\n                      <jats:sup>2<\/jats:sup>\n                      ,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001) also were significantly less in the ICE group than in the non\u2010ICE group. The incidence of postintervention nausea and vomiting (3.33%\u00a0vs. 19.48%,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.032), and hypotension (3.33%\u00a0vs. 18.83%,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.033) was significantly lower in the ICE group than in the non\u2010ICE group. Furthermore, the proportion using amiodarone in the first 3 months during follow\u2010up was significantly lower for the ICE group than for the non\u2010ICE group (40.00%\u00a0vs. 63.64%,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.024), and the rate of late recurrence remained unchanged in the ICE group, while there was a trend toward an increase in the rate of late recurrence in the non\u2010ICE group. One year after the operation, the success rates of AF ablation in the ICE group and non\u2010ICE group were 80.00% and 77.92%, and the difference between the groups was not statistically significant (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.825).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>ICE\u2010guided radiofrequency catheter ablation is safe and effective in the treatment of AF, and it has potential advantages in terms of ablation time, radiation exposure, complication occurrence, and patient prognosis.<\/jats:p>\n                  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