{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:46Z","timestamp":1787702446253,"version":"build-2784847793"},"reference-count":37,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T00:00:00Z","timestamp":1750291200000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Right ventricular (RV) infarction complicates one\u2010third of inferior ST\u2010segment elevation myocardial infarctions (STEMI). Our aim was to evaluate RV function to assess its in\u2010hospital and long\u2010term prognostic value.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We enrolled 247 patients with inferior STEMI treated with primary angioplasty. Echocardiography was performed within 48 h and after 6 months, including RV myocardial performance index (RVMPI), RV fractional area change (RVFAC), tricuspid annular plane systolic excursion (TAPSE), RV global longitudinal strain (RVGLS), and pulmonary artery systolic pressure (PASP). Major adverse cardiac events (MACE) were reported during the 6\u2010month follow\u2010up. The patients were categorized into MACE and non\u2010MACE groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In patients with MACE, RV diastolic dysfunction occurred earlier as evidenced by lower E\u2032 wave velocity (5.8 \u00b1 1.03\u00a0vs. 9.1 \u00b1 2.8\u00a0cm\/s, <jats:italic>p<\/jats:italic> = 0.04) and higher E\/E\u2032 (10.1 \u00b1 3.1\u00a0vs. 6.1 \u00b1 2.3, <jats:italic>p<\/jats:italic> = 0.03). After 6 months, distorted RV geometry and RV systolic dysfunction, evidenced by lower RVFAC (32.2 \u00b1 3.6%\u00a0vs. 38.06 \u00b1 3.9%, <jats:italic>p<\/jats:italic> = 0.04), lower TAPSE (14.6 \u00b1 1.2\u00a0vs. 17.3 \u00b1 1.7\u00a0mm, <jats:italic>p<\/jats:italic> = 0.02), higher RVGLS (\u221214.5 \u00b1 2.6%\u00a0vs. \u221217.5 \u00b1 1.2%, <jats:italic>p<\/jats:italic> = 0.04), and higher PASP (29.8 \u00b1 3.2\u00a0vs. 24.1 \u00b1 2.2\u00a0mmHg, <jats:italic>p<\/jats:italic> = 0.01), were reported later on. Multivariate analysis documented E\u2032 wave velocity, E\/E\u2032, RVFAC, and TAPSE as strong predictors of MACE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In inferior STEMI, RV diastolic dysfunction occurs earlier in patients with MACE. However, RV systolic dysfunction and impaired RV geometry develop later on. E\u2032 wave velocity, E\/E\u2032, RVFAC, and TAPSE are strong independent predictors of MACE.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.70223","type":"journal-article","created":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T10:20:37Z","timestamp":1750328437000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Prognostic Value of Right Ventricular Function Assessed by Echocardiography in Patients With Acute Inferior ST Elevation Myocardial Infarction"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3935-1505","authenticated-orcid":false,"given":"Hesham","family":"Refaat","sequence":"first","affiliation":[{"name":"Cardiology Department Zagazig University  Zagazig Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Arab","sequence":"additional","affiliation":[{"name":"Cardiology Department Zagazig University  Zagazig Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp492"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.12.036"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx393"},{"issue":"1","key":"e_1_2_8_5_1","first-page":"27","article-title":"Right Ventricular Myocardial Infarction: From Pathophysiology to Prognosis","volume":"18","author":"Ondrus T.","year":"2013","journal-title":"Experimental & Clinical Cardiology"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.81.2.401"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.10.056"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.4960230721"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.1810350105"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.09.2829"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.10.029"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000560"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.109.914366"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2009.01.018"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.2310\/JIM.0b013e3182857edf"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.08.1038"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw106"},{"key":"e_1_2_8_18_1","first-page":"2302","article-title":"Angiographic Assessment of Myocardial Reperfusion in Patients Treated With Primary Angioplasty for Acute Myocardial Infarction: Myocardial Blush Grade","volume":"97","author":"'t Hof A. W.","year":"1998","journal-title":"Zwolle Myocardial Infarction Study Group"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2014.10.003"},{"key":"e_1_2_8_20_1","first-page":"149","volume-title":"ASE's Comprehensive Echocardiography","author":"Goldstein S. A.","year":"2016"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.653576"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/2048872613490122"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4377-2698-5.00006-8"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01804-1"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2010.05.010"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2012.10.005"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfp204"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2003.028050"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.09.115"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(98)01000-5"},{"issue":"4","key":"e_1_2_8_31_1","first-page":"824","article-title":"Prognostic Value of Right Ventricular Function Assessed by Echocardiography in Patients Presenting With a First Acute ST Elevation Myocardial Infarction Treated by Primary PCI","volume":"120","author":"Zamfir D.","year":"2016","journal-title":"Revista Medico\u2010Chirurgicala A Societatii De Medici Si Naturalisti Din Iasi"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2009.171728"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2014.10.011"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0742-2822.2004.03139.x"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2011.12.035"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.112.967919"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(02)02612-7"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2012.01.009"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.70223","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T11:51:11Z","timestamp":1750765871000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.70223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1111\/echo.70223"],"URL":"https:\/\/doi.org\/10.1111\/echo.70223","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"2025-06-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70223"}}