{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T07:19:39Z","timestamp":1761290379591,"version":"build-2065373602"},"reference-count":22,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:00:00Z","timestamp":1759104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Radiofrequency catheter ablation (RFA) plays an increasing role in the treatment of ventricular arrhythmias (VAs). This study aimed to evaluate the echocardiographic and clinical characteristics of patients undergoing first\u2010time RFA for VAs and to identify risk factors associated with VA recurrence, implantable cardioverter\u2010defibrillator (ICD) therapy, and mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We studied patients scheduled for first\u2010time RFA for VAs from 2011 to 2022 with available transthoracic echocardiography before the procedure. The primary outcome was defined as VA recurrence, and the secondary outcome was defined as appropriate ICD therapy and mortality. Uni\u2010 and multivariable Cox hazards regression models were used to assess the prognostic value of cardiac structure and function by echocardiography.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 218 patients (mean age 61 years [\u00b115], 62% men, mean LVEF 51% [IQR: 44; 57]) underwent RFA during the study period. Of these, 90 patients (41%) had VA recurrence while 52 patients (24%) developed the secondary outcome during a median follow\u2010up time of 3.1 years (IQR: 1.1; 6.7 years). Patients with ventricular tachycardia had significantly more right\u2014and left ventricular (LV) dysfunction, compared to patients with premature ventricular contractions. No echocardiographic measures were associated with VA recurrence, while several echocardiographic measures were associated with the secondary outcome. LV mass index, LV ejection fraction, global longitudinal strain, and VA recurrence showed the highest predictive values of the secondary outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In patients undergoing RFA for VAs, several echocardiographic measures may identify patients at risk of an adverse outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/echo.70307","type":"journal-article","created":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T13:24:31Z","timestamp":1759152271000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Echocardiographic Markers of Prognosis in Patients Undergoing Ventricular Arrhythmia Ablation"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4110-3199","authenticated-orcid":false,"given":"Lisa Steen","family":"Duus","sequence":"first","affiliation":[{"name":"Department of Cardiology Herlev and Gentofte University Hospital University of Copenhagen  Copenhagen Denmark"},{"name":"Center For Translational Cardiology and Pragmatic Randomized Trials Department of Biomedical Sciences Faculty of Health and Medical Sciences University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Dons","sequence":"additional","affiliation":[{"name":"Department of Cardiology Herlev and Gentofte University Hospital University of Copenhagen  Copenhagen Denmark"},{"name":"Center For Translational Cardiology and Pragmatic Randomized Trials Department of Biomedical Sciences Faculty of Health and Medical Sciences University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morten Lock","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Cardiology Herlev and Gentofte University Hospital University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rene","family":"Worck","sequence":"additional","affiliation":[{"name":"Department of Cardiology Herlev and Gentofte University Hospital University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin H.","family":"Ruwald","sequence":"additional","affiliation":[{"name":"Department of Cardiology Herlev and Gentofte University Hospital University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arne","family":"Johannessen","sequence":"additional","affiliation":[{"name":"Department of Cardiology Herlev and Gentofte University Hospital University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jim","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Cardiology Herlev and Gentofte University Hospital University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tor","family":"Biering\u2010S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Department of Cardiology Herlev and Gentofte University Hospital University of Copenhagen  Copenhagen Denmark"},{"name":"Center For Translational Cardiology and Pragmatic Randomized Trials Department of Biomedical Sciences Faculty of Health and Medical Sciences University of Copenhagen  Copenhagen Denmark"},{"name":"Department of Cardiology University Hospital Rigshospitalet University of Copenhagen  Copenhagen Denmark"},{"name":"Steno Diabetes Center Copenhagen  Herlev Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,29]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.963371"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000005476"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.15420\/aer.2018.23.2"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000007403"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.000872"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehac262"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hjc.2017.11.017"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcha.2022.100962"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2014.10.003"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.118.006730"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.1061471"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.117.007045"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2016.2361"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13127"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.114.002155"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2022.10.024"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.655720"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.108.769471"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.07.013"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540\u20108167.2002.tb01965.x"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwk052"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.11.041"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.70307","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T07:14:36Z","timestamp":1761290076000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.70307"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,29]]},"references-count":22,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1111\/echo.70307"],"URL":"https:\/\/doi.org\/10.1111\/echo.70307","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"type":"print","value":"0742-2822"},{"type":"electronic","value":"1540-8175"}],"subject":[],"published":{"date-parts":[[2025,9,29]]},"assertion":[{"value":"2025-07-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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