{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T23:57:37Z","timestamp":1785455857581,"version":"3.56.0"},"reference-count":31,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T00:00:00Z","timestamp":1763510400000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004612","name":"Funda\u00e7\u00e3o Arauc\u00e1ria","doi-asserted-by":"publisher","award":["CP20\/2018PPP"],"award-info":[{"award-number":["CP20\/2018PPP"]}],"id":[{"id":"10.13039\/501100004612","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To investigate the effects of an 8\u2010weeks of high\u2010intensity interval training (HIIT) or moderate\u2010intensity continuous training (MICT) program on ventricular\u2010arterial coupling (VAC) in young women with obesity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Twenty\u2010four obese women completed an 8\u2010week supervised aerobic training program (3 sessions\/week) assigned to either HIIT (\n                      <jats:italic>n<\/jats:italic>\n                      = 11) or MICT (\n                      <jats:italic>n<\/jats:italic>\n                      = 13). The HIIT protocol involved four 4\u2010min bouts at 85%\u201395% of the maximum heart rate (HR\n                      <jats:sub>max<\/jats:sub>\n                      ), while the MICT consisted of continuous walking\/running for 41 min at 65%\u201375% of HR\n                      <jats:sub>max<\/jats:sub>\n                      . VAC was assessed using two methods: (1) the ratio of pulse wave velocity to global longitudinal strain (PWV\/GLS), and (2) the ratio of arterial to ventricular elastance (E\n                      <jats:sub>a<\/jats:sub>\n                      \/E\n                      <jats:sub>es<\/jats:sub>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Both HIIT (\u22120.35 \u00b1 0.01 to \u22120.31 \u00b1 0.05 m\/s%;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.005) and MICT (\u22120.35 \u00b1 0.01 to \u22120.30 \u00b1 0.05 m\/s%;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.003) significantly improved the PWV\/GLS ratio. However, only HIIT led to a significant reduction in the E\n                      <jats:sub>a<\/jats:sub>\n                      \/E\n                      <jats:sub>es<\/jats:sub>\n                      ratio (0.88 \u00b1 0.07 to 0.80 \u00b1 0.09\u00a0mmHg\/mL;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.024), with a significant correlation between relative changes in PWV\/GLS and E\n                      <jats:sub>a<\/jats:sub>\n                      \/E\n                      <jats:sub>es<\/jats:sub>\n                      ratio (\n                      <jats:italic>r<\/jats:italic>\n                      = 0.749;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.008).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Both HIIT and MICT improved VAC as assessed by PWV\/GLS ratio in young obese women. In contrast, elastance\u2010derived improvements (E\n                      <jats:sub>a<\/jats:sub>\n                      \/E\n                      <jats:sub>es<\/jats:sub>\n                      ) were observed only following HIIT. These findings suggest that PWV\/GLS may serve as a more sensitive and integrative marker for detecting exercise\u2010induced improvements in VAC.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/echo.70355","type":"journal-article","created":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T16:24:17Z","timestamp":1763569457000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["High\u2010Intensity Interval Training and Moderate\u2010Intensity Continuous Training on Ventricular\u2010Arterial Coupling (VAC) in Young Women With Obesity"],"prefix":"10.1111","volume":"42","author":[{"given":"Caroline Ferraz","family":"Sim\u00f5es","sequence":"first","affiliation":[{"name":"Research Group on Systemic Arterial Hypertension Arterial Stiffness and Vascular Aging  Maringa Brazil"},{"name":"Cesumar University  Maringa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rog\u00e9rio Toshiro Passos","family":"Okawa","sequence":"additional","affiliation":[{"name":"Research Group on Systemic Arterial Hypertension Arterial Stiffness and Vascular Aging  Maringa Brazil"},{"name":"Department of Medicine State University of Maringa  Maringa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6843-4150","authenticated-orcid":false,"given":"Jo\u00e3o Carlos","family":"Locatelli","sequence":"additional","affiliation":[{"name":"Research Group on Systemic Arterial Hypertension Arterial Stiffness and Vascular Aging  Maringa Brazil"},{"name":"School of Human Sciences (Sport Science, Exercise and Health) The University of Western Australia  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo Henrique","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Research Group on Systemic Arterial Hypertension Arterial Stiffness and Vascular Aging  Maringa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Higor Barbosa","family":"Reck","sequence":"additional","affiliation":[{"name":"Research Group on Systemic Arterial Hypertension Arterial Stiffness and Vascular Aging  Maringa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucimere","family":"Bohn","sequence":"additional","affiliation":[{"name":"Faculty of Sport University of Porto  Porto Portugal"},{"name":"Research Centre for Physical Activity Health and Leisure  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Mota","sequence":"additional","affiliation":[{"name":"Faculty of Sport University of Porto  Porto Portugal"},{"name":"Research Centre for Physical Activity Health and Leisure  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendell Arthur","family":"Lopes","sequence":"additional","affiliation":[{"name":"Research Group on Systemic Arterial Hypertension Arterial Stiffness and Vascular Aging  Maringa Brazil"},{"name":"Research Centre for Physical Activity Health and Leisure  Porto Portugal"},{"name":"Department of Physical Education State University of Maringa  Maringa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehae508"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaf216"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.109.131870"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1436"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/eci.13049"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.119.015716"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2020.111694"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1249\/JES.0000000000000100"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0110034"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-022-04931-5"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/17461391.2017.1359679"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41366-024-01586-4"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41440-020-0477-2"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00056.2018"},{"issue":"2","key":"e_1_2_11_16_1","first-page":"5","article-title":"Questin\u00e1rio internacional de atividade f1sica (IPAQ): Estudo de Validade e Reprodutibilidade no Brasil","volume":"6","author":"Matsudo S.","year":"2001","journal-title":"Revista Brasileira de Atividade F\u00edsica & Sa\u00fade"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2018.06.004"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000452448"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2022.03.024"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/14779072.2021.1955351"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/08037051.2025.2457698"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.116.004903"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2018.00135"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.154"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsams.2018.09.228"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2013-092576"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.114.03696"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2023.04.010"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.70172"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jead342"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.14854"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2020-102955"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.70355","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/echo.70355","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.70355","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:58:49Z","timestamp":1785452329000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.70355"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":31,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1111\/echo.70355"],"URL":"https:\/\/doi.org\/10.1111\/echo.70355","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"2025-09-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70355"}}