{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:32:23Z","timestamp":1772998343969,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T00:00:00Z","timestamp":1771286400000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study investigated the relationship between mitral stenosis (MS) severity and B\u2010line counts on lung ultrasonography (US) and their predictive value for PMBV requirement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 105 patients (70 MS, 35 controls) underwent transthoracic echocardiography (ECHO) and lung US using a 28\u2010point protocol. Patients performed an exercise test to 85% of their predicted heart rate, followed by repeat imaging. B\u2010line changes were analyzed by MS severity and symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      MS patients had significantly more B\u2010lines than controls (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). No significant difference was found between mild and moderate\u2010severe MS at baseline. In moderate\u2010severe MS, symptomatic patients had more B\u2010lines than asymptomatic patients, both at rest and post\u2010exercise (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.02 and\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.002, respectively). An increase &gt;3 B\u2010lines in the left hemithorax after exercise predicted percutaneous mitral balloon valvuloplasty (PMBV) with 85.7% sensitivity and 66.2% specificity (AUC 0.69,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.006).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Lung US assessment of B\u2010lines may assist in determining the optimal timing for intervention in MS, particularly in asymptomatic severe and symptomatic mild\u2010to\u2010moderate cases, where conventional ECHO findings may be inconclusive.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/echo.70360","type":"journal-article","created":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T14:16:08Z","timestamp":1771337768000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Importance of Lung Ultrasonography in the Assessment of Severity of Mitral Stenosis"],"prefix":"10.1111","volume":"43","author":[{"given":"Nergiz","family":"Aydin","sequence":"first","affiliation":[{"name":"Department of Cardiology TC Saglik Bakanligi Safranbolu Devlet Hastanesi  Karab\u00fck Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sefa","family":"Tatar","sequence":"additional","affiliation":[{"name":"Department of Cardiology Necmettin Erbakan University Faculty of Medicine  Konya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazire Belgin","family":"Akilli","sequence":"additional","affiliation":[{"name":"Emergency Medicine Department Konya City Hospital  Konya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunus Emre","family":"Yavuz","sequence":"additional","affiliation":[{"name":"Department of Cardiology Necmettin Erbakan University Faculty of Medicine  Konya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakan","family":"Akilli","sequence":"additional","affiliation":[{"name":"Department of Cardiology Necmettin Erbakan University Faculty of Medicine  Konya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,17]]},"reference":[{"key":"e_1_2_11_2_1","first-page":"1460","volume-title":"Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine","author":"Otto C. M.","year":"2022"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.2459\/JCM.0000000000000515"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08\u20101811"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000923"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11739\u2010022\u201002943\u20109"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2021.08.009"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2022.838479"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab368"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2019.07.008"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jead007"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.119.010269"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.05.019"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab395"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.70360","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/echo.70360","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.70360","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:48:18Z","timestamp":1772988498000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.70360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1111\/echo.70360"],"URL":"https:\/\/doi.org\/10.1111\/echo.70360","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"2025-09-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70360"}}