{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T16:43:48Z","timestamp":1786293828074,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2026,6]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objective<\/jats:title>\n To evaluate the corrected index of cardio\u2010electrophysiological balance (ICEBc) and left ventricular mechanical dispersion (LVMD), in obese individuals and to examine their associations with obesity severity and electromechanical myocardial heterogeneity.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n This prospective case\u2013control study included obese individuals (BMI \u226530\u00a0kg\/m\n 2<\/jats:sup>\n ) and normal\u2010weight healthy controls. All participants underwent standard 12\u2010lead electrocardiography and transthoracic echocardiography. The ICEB and corrected ICEB (ICEBc) were calculated from ECG recordings. LVMD was assessed using two\u2010dimensional speckle\u2010tracking echocardiography. Comparisons between groups and correlation analyses between ICEBc, LVMD, and body mass index (BMI) were performed using appropriate statistical methods, with\n p<\/jats:italic>\n < 0.05 considered statistically significant.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Obese individuals had higher systolic and diastolic blood pressures. LVMD was significantly higher and global longitudinal strain was significantly lower in obese participants. QTc and ICEBc were significantly higher in obesity. Among obese subgroups, LVMD and ICEBc increased with obesity severity. LVMD showed a good positive correlation with ICEBc (\n r<\/jats:italic>\n = 0.675,\n p<\/jats:italic>\n < 0.001). BMI correlated moderately with LVMD (\n r<\/jats:italic>\n = 0.543,\n p<\/jats:italic>\n < 0.001) and weakly with ICEBc (\n r<\/jats:italic>\n = 0.257,\n p<\/jats:italic>\n = 0.021).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Obesity was associated with higher LVMD and ICEBc values, suggesting increased electrical and mechanical myocardial heterogeneity. LVMD and ICEBc may serve as complementary, non\u2010invasive surrogate markers of obesity\u2010related electromechanical remodeling. Larger longitudinal studies with rhythm monitoring are required to determine whether these parameters predict clinical arrhythmic events.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/echo.70529","type":"journal-article","created":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T15:22:03Z","timestamp":1781018523000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of Index of Cardio\u2010Electrophysiological Balance and Left Ventricular Mechanical Dispersion in Obese Individuals"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4533-9799","authenticated-orcid":false,"given":"Fatih","family":"Guven","sequence":"first","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine Inonu University Malatya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7502-6534","authenticated-orcid":false,"given":"Yakup","family":"Yigit","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine Malatya Turgut Ozal University Malatya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5184-5308","authenticated-orcid":false,"given":"Yucel","family":"Karaca","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine Inonu University Malatya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4740-4371","authenticated-orcid":false,"given":"Mehmet","family":"Cansel","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine Inonu University Malatya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6523-9130","authenticated-orcid":false,"given":"Adil","family":"Bayramoglu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine Inonu University Malatya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9944-6994","authenticated-orcid":false,"given":"Emre","family":"Sonmez","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine Inonu University Malatya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,9]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"13","article-title":"GBD 2015 Obesity Collaborators. 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