{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:25:06Z","timestamp":1786987506269,"version":"build-2736575974"},"reference-count":44,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Cardiac shear wave elastography (SWE) is an emerging ultrasound\u2010based technique that enables noninvasive assessment of myocardial mechanical properties beyond conventional motion\u2010 and deformation\u2010based indices. By tracking the propagation of shear waves within the myocardium using ultrafast imaging, SWE provides stiffness\u2010related information that may complement standard echocardiographic parameters in selected clinical settings. In this narrative review, we summarize the methodological principles of cardiac SWE, including acoustic radiation force\u2010induced techniques, natural shear wave imaging approaches, and emerging three\u2010dimensional SWE. We discuss current clinical evidence in key disease states characterized by altered myocardial stiffness, such as hypertrophic cardiomyopathy, cardiac amyloidosis, heart failure with preserved ejection fraction, and post\u2010transplant or diffuse myocardial injury. Importantly, SWE measurements are highly context\u2010dependent and influenced by cardiac phase, loading conditions, myocardial anisotropy, imaging plane, and acquisition methodology. Therefore, reported values should be interpreted as reflecting stiffness\u2010related myocardial behavior rather than direct measures of fibrosis or specific histopathologic substrates. At present, cardiac SWE remains primarily a research\u2010stage technique, with potential roles in phenotypic characterization, disease burden assessment in selected populations, longitudinal monitoring, and future integration into multiparametric echocardiographic and artificial intelligence\u2013assisted workflows. Further standardization, definition of normal reference ranges, technical validation, and multicenter clinical studies are required before broader clinical adoption. In conclusion, cardiac SWE represents a promising extension of echocardiographic assessment of myocardial mechanics, but its clinical interpretation requires careful consideration of methodological, physiological, and disease\u2010specific determinants.<\/jats:p>","DOI":"10.1111\/echo.70551","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T15:06:24Z","timestamp":1783955184000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cardiac Shear Wave Elastography: Principles, Clinical Applications, and Practical Considerations for Interpretation"],"prefix":"10.1111","volume":"43","author":[{"given":"Fan","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Ultrasound The First Affiliated Hospital of Shenzhen University The Second People's Hospital of Shenzhen  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiyao","family":"Xu","sequence":"additional","affiliation":[{"name":"Central Laboratory The First College of Clinical Medical Science China Three Gorges University &amp; Yichang Central People's Hospital  Yichang China"},{"name":"Cardiovascular Medicine The First College of Clinical Medical Science China Three Gorges University &amp; Yichang Central People's Hospital  Yichang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,13]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40885\u2010015\u20100035\u20104"},{"issue":"46","key":"e_1_2_12_3_1","first-page":"5307","article-title":"Hopeful Future for Echocardiography. 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