{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T20:21:38Z","timestamp":1787602898871,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Septal myectomy treats hypertrophic obstructive cardiomyopathy (HOCM), but its effect on myocardial deformation across cardiac chambers is incompletely defined. We evaluated chamber\u2010specific strain remodeling 1 year after septal myectomy and examined whether atrial strain was associated with atrial fibrillation (AF) during follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively studied 187 consecutive patients undergoing surgical septal myectomy for HOCM. Conventional echocardiography and speckle\u2010tracking strain analysis were used to assess left ventricular (LV), right ventricular (RV), left atrial (LA), and right atrial (RA) deformation preoperatively and at 1\u2010year follow\u2010up. Paired analyses compared preoperative and postoperative strain values. Multivariable logistic regression evaluated associations between baseline strain measures, AF, and all\u2010cause mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 187 patients, 85 had analyzable 1\u2010year strain studies. At 1 year, LA contractile strain (CS) improved from 10.4\u00b15.9% to 13.6\u00b17.1% (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.005), whereas LA reservoir strain (RS) did not significantly change. In contrast, RA\u2010RS decreased from 36.0\u00b110.6% to 28.0\u00b111.6% (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.001), RV free\u2010wall strain worsened from \u221226.3\u00b17.0% to \u221221.1\u00b16.8% (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.001), and RV global longitudinal strain (GLS) worsened from \u221221.3\u00b15.1% to \u221217.3\u00b15.5% (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.001). LV\u2010GLS was unchanged. Higher LA\u2010CS was associated with lower odds of AF after adjustment (aOR 0.92, 95% CI 0.85\u20130.99;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.018), as was higher LA\u2010RS (aOR 0.95, 95% CI 0.91\u20130.99;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.035). LA\u2010RS was associated with mortality in unadjusted analysis but not after multivariable adjustment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Septal myectomy is followed by nonuniform, chamber\u2010specific deformation remodeling. LA\u2010CS improves, LA\u2010RS and CS identify patients at higher AF risk, LV\u2010GLS remains unchanged, and right\u2010sided longitudinal deformation worsens at 1 year. Four\u2010chamber strain analysis may augment post\u2010myectomy surveillance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/echo.70567","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T14:56:20Z","timestamp":1785250580000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Four\u2010Chamber Deformation Remodeling and Atrial Fibrillation After Septal Myectomy for Obstructive Hypertrophic Cardiomyopathy"],"prefix":"10.1111","volume":"43","author":[{"given":"Olga N.","family":"Kislitsina","sequence":"first","affiliation":[{"name":"Division of Cardiac Surgery Feinberg School of Medicine and the Bluhm Cardiovascular Institute Northwestern University  Chicago Illinois USA"},{"name":"Division of Cardiology Feinberg School of Medicine and the Bluhm Cardiovascular Institute Northwestern University  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lubna","family":"Choudhury","sequence":"additional","affiliation":[{"name":"Division of Cardiology Feinberg School of Medicine and the Bluhm Cardiovascular Institute Northwestern University  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kifah","family":"Hussain","sequence":"additional","affiliation":[{"name":"Division of Cardiology Feinberg School of Medicine and the Bluhm Cardiovascular Institute Northwestern University  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James D.","family":"Thomas","sequence":"additional","affiliation":[{"name":"Division of Cardiology Feinberg School of Medicine and the Bluhm Cardiovascular Institute Northwestern University  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seokyung","family":"An","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery Feinberg School of Medicine and the Bluhm Cardiovascular Institute Northwestern University  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail S.","family":"Baldridge","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery Feinberg School of Medicine and the Bluhm Cardiovascular Institute Northwestern University  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J.","family":"Romary","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery Feinberg School of Medicine and the Bluhm Cardiovascular Institute Northwestern University  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth","family":"Whippo","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery Feinberg School of Medicine and the Bluhm Cardiovascular Institute Northwestern University  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James L.","family":"Cox","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery Feinberg School of Medicine and the Bluhm Cardiovascular Institute Northwestern University  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick M.","family":"McCarthy","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery Feinberg School of Medicine and the Bluhm Cardiovascular Institute Northwestern University  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas R.","family":"Johnston","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery Feinberg School of Medicine and the Bluhm Cardiovascular Institute Northwestern University  Chicago Illinois 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