{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T09:00:16Z","timestamp":1790586016963,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Diagnosis of left ventricular diastolic dysfunction (LVDD) in the context of septic shock is challenging. We aimed to compare different algorithms applied to septic patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Secondary analysis of a prospective, single\u2010center study of 98 consecutive adult septic shock patients undergoing comprehensive speckle\u2010tracking echocardiography within 24\u00a0h of ICU admission. We studied the prevalence and the prognostic value of five LVDD diagnostic algorithms:2016\u2010American Society of Echocardiography (ASE)\/European Association CardioVascular Imaging(EACVI), 2024\u2010British Society of Echocardiography(BSE), 2025\u2010ASE, Lanspa\u2010simplified criteria, and a further Lanspa\u2010modified version hereby proposed (adding LVDD diagnosis when LV ejection fraction&lt; 50%, as in 2016\u2010ASE\u2010EACVI guidelines). Logistic regression and Kaplan\u2010Meier curves were used to explore the association between algorithms and 30\u2010day mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The prevalence of LVDD on day 1 varied widely, ranging from 32.7%(Lanspa) to 72.4%(2024\u2010BSE). Concordance between the three cardiology guidelines ranged from slight to moderate: the lowest agreement among them was observed between the 2016\u2010ASE\/EACVI and the 2025\u2010ASE criteria(55.1%, Kappa 0.10), whereas the highest agreement across all five algorithms was seen between the 2016\u2010ASE\/EACVI and the Lanspa\u2010modified criteria(88.8%, Kappa 0.77). When correcting for severity score, need for invasive ventilation, and norepinephrine dose, independent prognostic values for 30\u2010day mortality were observed only for the 2025\u2010ASE, the Lanspa and the Lanspa\u2010modified algorithms, but all algorithms had similar predictive performances.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The prevalence of LVDD in septic shock is highly dependent on the diagnostic algorithm utilized. Although only the 2025\u2010ASE, Lanspa, and Lanspa\u2010modified algorithms demonstrated independent prognostic value after multivariable adjustment, prognostic discrimination for 30\u2010day mortality was moderate and comparable across all approaches.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/echo.70638","type":"journal-article","created":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T02:13:50Z","timestamp":1790388830000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of Left Ventricular Diastolic Dysfunction and Prognostic Value in Septic Shock Patients According to Different Guidelines: Comparison Between Contemporary Cardiological Algorithms and Simplified Approaches"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8539-1092","authenticated-orcid":false,"given":"Filipe A.","family":"Gonzalez","sequence":"first","affiliation":[{"name":"Centro Cardiovascular Da Universidade de Lisboa CCUL@RISE Faculdade De Medicina Universidade De Lisboa  Lisboa Portugal"},{"name":"Intensive Care Unit of Hospital CUF Tejo  Lisboa Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0600-4427","authenticated-orcid":false,"given":"\u00c9rico","family":"Costa","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine Unidade Local de Sa\u00fade de Gaia e Espinho  Vila Nova de Gaia Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7724-2830","authenticated-orcid":false,"given":"Deborah","family":"Rondinella","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Intensive Care \u201cPoliclinico\u2010San Marco\u201d University Hospital  Catania Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5144-0776","authenticated-orcid":false,"given":"Filippo","family":"Sanfilippo","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Intensive Care \u201cPoliclinico\u2010San Marco\u201d University Hospital  Catania Italy"},{"name":"Department of General Surgery and Medical\u2010Surgical Specialties Section of Anesthesia and Intensive Care University of Catania  Catania 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