{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T03:56:46Z","timestamp":1790827006175,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS) remain recommended for cardiotoxicity surveillance during cancer therapy, yet it changes late and overlooks injury to the other cardiac chambers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>We systematically reviewed echocardiographic and cardiac magnetic resonance (CMR) studies that assessed left atrial (LA), right atrial (RA), and right ventricular (RV) function in patients exposed to potentially cardiotoxic oncological treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>PubMed, Scopus, Web of Science, and the Cochrane Central Register of Controlled Trials were searched for English\u2010language studies published between January 2020 and March 2026, following the PRISMA recommendations. Across tumor types\u2014lymphoma, acute lymphoblastic leukemia, breast, gastrointestinal, and melanoma\u2014and across anthracycline\u2010, trastuzumab\u2010, fluoropyrimidine\u2010, and immune checkpoint inhibitor\u2013based regimens, strain imaging detected subclinical dysfunction that conventional measures missed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>LA reservoir strain declined early and frequently preceded any fall in LVEF, outperforming volumetric LA indices for the detection and prediction of cancer therapy\u2013related cardiac dysfunction (CTRCD). RV deformation parameters, particularly free\u2010wall longitudinal strain and three\u2010dimensional RV ejection fraction, identified RV involvement that was sometimes independent of LV cardiotoxicity and was associated with adverse cardiac events. Data on the RA remain sparse but point in the same direction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Multichamber strain assessment adds sensitivity to LVEF and GLS\u2010based monitoring; standardization of acquisition, reference values, and reporting is needed before it can enter routine cardio\u2010oncology surveillance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/echo.70642","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T03:19:08Z","timestamp":1790824748000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Not Only the Left Ventricle: The Impact of Potentially Cardiotoxic Oncological Treatment on the Left Atrium and Right Ventricle"],"prefix":"10.1111","volume":"43","author":[{"given":"Maria","family":"\u017bak","sequence":"first","affiliation":[{"name":"Students Research Group, Faculty of Medical Sciences in Zabrze Medical University of Silesia  Katowice Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Suchodolski","sequence":"additional","affiliation":[{"name":"First Department of Cardiology and Angiology Silesian Center for Heart Diseases  Zabrze Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz","family":"Niklewski","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Transplantology and Vascular Surgery, Faculty of Medical Sciences in Zabrze Medical University of Silesia  Katowice Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariola","family":"Szulik","sequence":"additional","affiliation":[{"name":"Students Research Group, Faculty of Medical Sciences in Zabrze Medical 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