{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T03:56:35Z","timestamp":1790826995982,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2026,10]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n Left ventricular hypertrophy (LVH) constitutes Stage B heart failure and marks elevated risk for atrial fibrillation, stroke, and death. Unlike body mass index, body roundness index (BRI), derived from waist circumference and height, more accurately reflects visceral adiposity. Because existing BRI\u2013LVH evidence is usually cross\u2010sectional, we investigated whether the BRI trajectory can predict incident LVH.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Of a total of 2,578 subjects who underwent echocardiographic examinations, we studied 1,764 participants who were free of LVH on echocardiography at baseline (2007\u20132008, wave 4). BRI trajectory was determined from BRI values measured at four biennial examinations (2001\u20132008). The outcome was incident LVH on echocardiography during the follow\u2010up (2009\u20132016, wave 5\u20138).<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The mean age was 53.2\u00b16.3 years, and 828 (46.9%) were women. Latent class mixed models identified 3 sex\u2010specific BRI trajectory classes: stable\u2010low (Class 1), stable\u2010moderate (Class 2), and variable\u2010high BRI (Class 3). Among men, 225 (24.0%), 615 (65.7%), and 96 (10.3%) were classified into these classes, respectively; among women, 319 (38.5%), 356 (43.0%), and 153 (18.5%). Incident LVH, defined as LVH on echocardiography at any of the 4 follow\u2010up examinations conducted during 2009\u20132016 (wave 5\u20138), developed in 249 of 936 men (26.6%) and 196 of 828 women (23.7%), and incidence increased across trajectory classes in both sexes (in men, 5.8%, 30.6%, and 50.0%; in women, 7.5%, 32.3%, and 37.3%; both\n P<\/jats:italic>\n < 0.001). In the fully adjusted model, compared with Class 1, OR of incident LVH were increased for Class 2 (men; 4.75 [95% CI, 2.33\u20139.66]; women, 4.53 [2.67\u20137.68]; both\n P<\/jats:italic>\n < 0.001) and for Class 3 (men, 9.28 [3.91\u201322.02]; women, 4.60 [2.50\u20138.48]; both\n P<\/jats:italic>\n < 0.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n In a community\u2010based Korean cohort, sex\u2010specific BRI trajectories characterized by stable\u2010moderate (Class 2) or variable\u2010high (Class 3) BRI trajectory groups were associated with a substantially increased risk of incident LVH in both men and women.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/echo.70644","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T03:18:26Z","timestamp":1790824706000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Body Roundness Index Trajectories and Incident Left Ventricular Hypertrophy: Results of a Community\u2010Based Study in Korea"],"prefix":"10.1111","volume":"43","author":[{"given":"Jae\u2010Hyeong","family":"Park","sequence":"first","affiliation":[{"name":"Department of Cardiology in Internal Medicine School of Medicine Chungnam National University Chungnam National University Sejong Hospital Sejong South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan Hee","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine Korea University Ansan Hospital Ansan South Korea"},{"name":"Institute of Human Genomic Study, College of Medicine Korea University Ansan Hospital Ansan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soon\u2010Ki","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine Chungnam National University Hospital Daejeon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong Hwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine Korea University Ansan Hospital Ansan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"issue":"1","key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1093\/eurheartj\/ehaf524","article-title":"Left Ventricular Hypertrophy and Myocardial Fibrosis in Heart Failure With Preserved Ejection Fraction: Mechanisms and Treatment","volume":"47","author":"Peikert A.","year":"2026","journal-title":"European Heart Journal"},{"issue":"18","key":"e_1_2_7_3_1","first-page":"e895","article-title":"AHA\/ACC\/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"145","author":"Heidenreich P. 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A.","year":"2023","journal-title":"European Heart Journal"},{"issue":"11","key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1016\/j.amjcard.2016.03.020","article-title":"Electrocardiographic Left Ventricular Hypertrophy as a Predictor of Cardiovascular Disease Independent of Left Ventricular Anatomy in Subjects Aged \u226565 Years","volume":"117","author":"Leigh J. A.","year":"2016","journal-title":"American Journal of Cardiology"},{"issue":"16","key":"e_1_2_7_7_1","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.011897","article-title":"Inappropriate Left Ventricular Mass and Cardiovascular Disease Events and Mortality in Blacks: The Jackson Heart Study","volume":"8","author":"Anstey D. 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